The second game of the ''Majin Tensei'' series of {{Strategy RPG}}s.

In 1996, a demonic infestation arises in Tokyo lead by someone who overthrows the government in a coup d' etat, turning the city into a demon paradise as a result. An organization known as Partisan is created to fight back against this individual and unravel his Modus Operandi, but before long the situation goes out of control.

Main Characters:
* Naoki Takeuchi (Protagonist): Compared to others in the Megaten Franchise, he can actually talk. Uses Swords, Knives, and Firearms.
* Kaoru Tachibana: TheBigGuy of the group, both physically and magically. Specializes in Katana and Axe use, learns Agi, Zio, Giga, and Megido spells.
* Tomoharu Kikuchi: TheSmartGuy of the group. [[spoiler: He gains the ability to summon demons later on.]] Can use Swords, Knives, and Bows.
* Aya Kikuchi: ActionGirl of the group, can use some offensive magic but specializes in healing. Uses Knives, Firearms, and Staves, learns Dia, Maragi, and Rimudora spells.
* Karen Rose: A mysterious woman who appears in Naoki's dreams, she apparently knows what's causing the problems in Tokyo. [[spoiler: Can use Knives, Spears and Firearms, but only joins the party on any non-Neutral route.]]
* Ogiwara: [[spoiler: The leader of the demonic invasion. Can use Swords, Katanas, and Firearms, but only joins on a Neutral route. He is said to be the child of Lucifer himself, which is why he can talk to demons.]]

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!This game contains the following tropes:
* ArcWords: Nemesis, it's even mentioned in the title as Spiral Nemesis.
* AttractiveBentGender: [[spoiler: Beelzebub]].
* BrainwashedAndCrazy: [[spoiler: Tomoharu as a result of exposure to the DIO system]].
* CharacterAlignment: Perhaps the first Megaten game that allows humans to be Light or Dark Aligned along with Law or Chaos, this affects which demons you can summon.
* FinalDeath: Any demons who die will stay dead and can't be revived.
* FunWithAcronyms: DIO, FRI-DAY, and so on.
* GiantSpaceFleaFromNowhere: [[spoiler: Ahriman on the Neutral Route, also doubles as the TrueFinalBoss story wise]].
* IsometricProjection: This is the only isometric game in the ''Majin Tensei'' subseries.
* MultipleEndings: 5 of them, all based on your alignment.
* [[spoiler: MyFutureSelfAndMe: The Dark-Chaos Ending]]
* MythologyGag: References from the first game are in this. [[spoiler: Even some of the music; Devil Dance is used for the Free missions (Purple marks) on the map, Frame Up Fragment is used on the Paranoia maps, and the Satellite map uses Bicarbonate of Face/Fate (Overworld theme of ''Majin Tensei''). In addition the Core of Megapolis is a [[ShinMegamiTenseiII metal pyramid with the top removed]]]]
* NamesTheSame: Naoki Takeuchi from this game, Naoki Konishi from ''{{Persona 4}}'', and Naoki Kashima, the [[ShinMegamiTenseiNocturne Demi-Fiend's/Hito-Shura's]] name from the radio play. Also, Kaoru Tachibana from this game, and [[{{Persona2}} Kaoru Saga]].
* NoExportForYou: Much like the first and 3rd ''MajinTensei'' games, this wasn't ported to the US.
* RareCandy: Much like the other Megaten games, Incenses are in this one. However they cannot be used outside of battle maps.
* [[spoiler:ResetButtonEnding]]: The [[spoiler:Dark-Law ending]].
* [[spoiler:TemporalParadox: Karen's goal is to go into the past to prevent anything from interfering with Megapolis' origin.]]
* TooAwesomeToUse: The Moon Skins recruit demons immediately when used, no negotiation needed. You can even get demons opposite your alignment this way.
* TouchedByVorlons: Kaoru and Aya learn the ability to use magic from [[spoiler: Amnesia, a magical realm]].
* TimeTravel: To several periods in the future, even one year in time before the first scenario.
* WeCannotGoOnWithoutYou: If any of your humans die, game over.
* [[spoiler:WellIntentionedExtremist: Ogiwara. He led a faction of demons of his own to repel demons from Paranoia that would have destroyed modern civilization in 1996.]]
* WingedHumanoid: Some demons, angels, and [[spoiler: Satan and Lucifer, are fought as their humanoid forms rather than their transformed states in earlier and later games in the Megaten franchise.]]
* {{Zoroastrianism}}: Perhaps the first game in the franchise that features Ahura Mazda in his original form and Mithra along with [[spoiler: Ahriman]].
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