''Life and Death'' is a medical simulation game released by The Software Toolworks (who would eventually go on to make ''Videogame/MarioIsMissing'' and ''Mario's Time Machine'') for the [[UsefulNotes/IBMPersonalComputer PC]] and {{Mac}} in 1988, with ports to the UsefulNotes/{{Amiga}}, UsefulNotes/AtariST, and [[UsefulNotes/AppleII Apple IIGS]] following years later. You must diagnose and operate on patients. It is generally known for its painstaking realism in surgery and overall difficulty.

It was followed by ''Life and Death II: The Brain''. Playing a brain surgery sim is more like running through a very long, difficult checklist than anything, but drat if using a bone drill on a patient's skull isn't more tense than some entire survival horror games.

Some gameplay footage can be found [[http://www.youtube.com/watch?v=sczxk0IkcVY here]].
!!This game contains examples of:
* AutopsySnackTime: In the second game whenever a patient dies, the morgue staff will be eating a pizza in front of it.
* {{Feelies}}: The first game not only comes with a booklet on the history of surgery, but it also includes a surgical mask and pair of latex gloves.
* FunnyBackgroundEvent: In the second game, go into the lounge. You can see someone endlessly pouring coffee into a cup until it overflows.
* SpiritualSuccessor: The ''VideoGame/TraumaCenter'' games are pretty much this.
* UltimateJobSecurity: No matter how many times you screw up, you simply get sent back to med school.
* VideoGameCrueltyPotential: Oh so much. You can slice open your patient with the scalpel without anesthetizing them first, causing them to scream in pain; you can dope them up with antibiotics and anaesthetics until they die; among other things.
* WhatTheHellPlayer: During examination, if you poke a patient in their painful areas enough times (where they yelp in pain), they start to get tired and wonder whether or not you're a real doctor.
** If you do all sorts of stuff the game makes sure to yell at you. Screw up during brain surgery, then they start giving you a bunch of hysterical people, drug addicts, people with neuropathy and migraines before getting a surgery.
** Pick up the pin. Click on the patient's eye. Your director then says, "The staff was not amused by your impression of [[Franchise/ANightmareOnElmStreet Freddy Krueger]]."
** Multiple cuts on a single layer? Nice going, Jack the Ripper.