* HeyItsThatGuy: The penultimate episode features [[Film/DieHard2 Will]][[Film/IronMan3 iam]] [[BillAndTedsBogusJourney Sad]][[Series/{{Wonderfalls}} ler]] as the VictimOfTheWeek that Tru attempts to save.
** KalPenn shows up in an early episode that's essentially [[WholePlotReference reuses]] the story of ''{{Flatliners}}''.
* MissingEpisode: The final episode wasn't seen by fans in America until Season 2 was released on DVD, because the season was postponed until spring (the episode was set around {{Christmas|Episode}}).
* OldShame: Zach Galifinakis apparently hated the show to the point that it caused him to be a huge {{Jerkass}} on the set. Creator/ElizaDushku is also said to have very mixed feelings regarding it.
* RetroactiveRecognition: One episode had [[Series/HowIMetYourMother Robin Scherbatsky]] attempting to frame Tru's brother in a plot to murder her estranged husband, [[Series/StargateAtlantis Colonel Sheppard.]]
** To say nothing of Davis, played by Zachary Galifinakis before he was widely known to the general public
** Tru's best friend is [[Series/CriminalMinds JJ]] and her major love interest in the first season, is none other than [[Series/WhiteCollar Neal Caffrey.]] Major connections to the FBI
** [[Series/GreysAnatomy Jeffrey]] [[Series/{{Supernatural}} Dean]] [[Film/{{Watchmen}} Morgan]] appears in one episode as one of the victims asking for Tru's help.
** One episode has Tru attempting to help a soldier see his estranged girlfriend one last time before his death. Did I mention that said girlfriend happens to be [[Film/ScottPilgrimVsTheWorld Ramona Flowers]]?
*** Not to mention said soldier is [[Series/{{TrueBlood}} Jason Stackhouse]]
** Tru's professor boyfriend cheats on her with [[Series/{{RookieBlue}} Andy McNally]]
* ScrewedByTheNetwork: Slotted against ''Series/{{CSI}}'' and ''Series/{{Survivor}}'', cancelled six episodes into the second season, which was then postponed for months - and then the final episode went completely unaired until the Sci-Fi channel picked up the series. One of the worst treatments of a good Spec-Fi show since ''Series/{{Firefly}}''... probably less surprising when you learn they aired about a year or two apart on the same network.
* WhatCouldHaveBeen: JensenAckles was originally going to play [[TheDanza Jensen]], but had to drop out due to his then-commitment to ''Series/{{Smallville}}''.
* WordOfGod: After the show was canceled, one screenwriter posted [[http://tightropegirl.livejournal.com/8190.html four liveblog journals]] detailing the direction the second season arcs were going.