* HeyItsThatVoice:
** Creator/PeterCullen is once again Optimus Prime.
** Creator/JohnnyYongBosch is Bumblebee.
** Creator/SteveBlum is the Narrator, Barricade, Shockwave, Cliffjumper, and Ramjet.
*** For his speaking appearance in the Gamestop commercial, Shockwave is reprised by Creator/CoreyBurton.
** Creator/NolanNorth is Brawl.
** Creator/RichardEpcar is Skywarp.
** Creator/SamRiegel is Starscream.
** Creator/TravisWillingham is Sideswipe and Hot Spot.
** Creator/CrispinFreeman is Breakdown and Grimlock.
** Creator/TroyBaker is Jetfire and Zeta Prime.
** Creator/KariWahlgren is Arcee.
** Creator/JamiesonPrice is Warpath and Ultra Magnus.
** Creator/PatrickSeitz is Silverbolt.
** Creator/LiamOBrien is Air Raid and Cyclonus.
** Creator/FredTatasciore is Ratchet (reprising the role from the tie-in game to [[Film/{{Transformers}} the first live-action movie]]), Megatron, Omega Supreme, Trypticon, and Motormaster.
** Creator/KeithSilverstein is Rumble and Frenzy.
** KeithSzarabajka is Ironhide.
** Creator/JessicaStraus ([[VideoGame/StreetFighterIV Juri Han]], [[VideoGame/{{Infamous}} Sasha]], [[EurekaSeven Gidget]]) is Slipstream.
** Isaac C. Singleton Jr. ([[Anime/{{Hellsing}} Incognito]], [[PiratesOfTheCaribbean Bo'sun]], [[VideoGame/StreetFighterIV Sagat]]) is Soundwave and [[spoiler: The Core of Cybertron/Primus]].
** Graham [=McTavish=] ([[Series/TwentyFour Mikhail Novakovich]], [[WesternAnimation/AvengersEarthsMightiestHeroes Lo]][[HulkVs ki]], [[VideoGame/{{Infamous}} Bertrand]]) is Thundercracker.
** Ed O'Ross is Kup.
*** This basically means the voice cast (with a few exceptions like Optimus, Megatron, Brawl, and Thundercracker to name a few) is a [[RelationshipVoiceActor semi]]-[[DotHackGUGames .hack//G.U.]] reunion.
** From the Italian dub: while Optimus Prime, Bumblebee and Ratchet have the same voices as their ''[[WesternAnimation/TransformersAnimated Animated]]'' selves, we have some ''WesternAnimation/BeastWars'' guys between the voices: Megatron and Starscream are Terrorsaur and Quickstrike. Also, Jetfire and Soundwave are respectively [[Anime/YuGiOh Tristan and Pegasus]], and Air Raid is [[DragonBall Piccolo]].
* IKnewIt: ''WesternAnimation/TransformersPrime'' is set in the same universe as "[=WfC=]'' and [[spoiler: during Ratchet's recap of the events during "One Shall Rise, Part 3" confirms that the being listed only as "Core" in the credits was indeed Primus.]]
* OldShame: Creator/CoreyBurton, who voiced Shockwave (SteveBlum does it in the game proper) in the DLC commercial for the game, said that the gag nature and rushed performance seemed OutOfCharacter and that he felt he [[InNameOnly barely sounded like Shockwave at all]].
* PlayingAgainstType:
** SamRiegel as Starscream.
** NolanNorth as Brawl.
* The class system was borrowed from a failed D20 based Transformers Game later published under the name Mechamoprhs.