* KeepCirculatingTheTapes: The 3rd and final season of the cartoon was never released on R1 DVD, and most likely never will be. Additionally, the two episodes from the first two seasons, "The Tick Vs. the Mole Men" and "Alone Together" were excluded from the DVD releases, which combined with the third season leaves 12 of the show's 36 episodes unavailable on DVD.
* TheOtherDarrin:
** After Season 1, Creator/RobPaulsen voiced Arthur for the rest of the series, replacing Micky Dolenz.
** After Paulsen took over as Arthur, Stuart Stone replaced him as the voice of Charles the Brainchild.
** The Breadmaster changed voice actors each appearance: in his debut episode he was voiced by Roddy [=McDowall=], in his second appearance he was voiced by Jess Harnell, and in his final appearance he was voiced by Martin Jarvis.
* {{Trope Namer|s}}: This series has named the following tropes:
** GravityIsAHarshMistress
** IfYoureSoEvilEatThisKitten
** NighInvulnerability
** NotInTheFace
* WhatCouldHaveBeen: If the creators found good enough footage, then The Tick could have appeared on ''WesternAnimation/SpaceGhostCoastToCoast''.
** There were plans to make a SpinOff series of the Chainsaw Vigilante, but never materialised.
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