* ActingForTwo: Of the main characters, Creator/FrankWelker voiced both Ray and Slimer. Welker would also voice a number of antagonists, such as the Bogeyman, Sandman and Samhain. Creator/MauriceLaMarche also voiced a number of roles, too. Lorenzo Music also voiced Peter's dad, with Dave Coulier taking over later. And since Laura Summer (who originally played Janine) is the only voice actress credited, she may well have played every female role in the series until she was replaced by Creator/KathSoucie.
* ActorAllusion:
** In "Victor the Happy Ghost," Peter refers to ''Series/TheBobNewhartShow'' as his favorite TV show. Lorenzo Music co-created the series.
** In "Jailbusters," the ghostly judge is voiced by [[Series/TheFreshPrinceOfBelAir James Avery]].
** The episode "Ghostbuster of the Year" (an episode long ''Film/CitizenKane'' reference) seems to have been produced solely to showcase Creator/MauriceLaMarche's impersonation of Creator/OrsonWelles.
** In "A Fright at the Opera", before the Diva selects Peter as her bodyguard, she states "I hate Mondays". Lorenzo Music's (Peter's voice actor) most famous role, [[WesternAnimation/GarfieldAndFriends Garfield]], also has a distaste for that particular day.
* ExecutiveMeddling: Despite its runaway success, Creator/{{ABC}} decided they needed to "fix" the show and hired a consulting firm named Q5 to take a look at it. According to Creator/JMichaelStraczynski, the head writer at the time, Q5 didn't do any audience research or focus testing but demanded changes based on what they themselves believed would made a cartoon successful. Janine was changed to be more feminine and meek, and received round glasses because it was claimed her pointy ones could scare children. More changes were forced upon the writing staff starting with Season 3. The Junior Ghostbusters, a group of [[KidAppealCharacter recurring child characters]], were added. More focus was placed on Slimer, who spun off into his own (doomed) cartoon in Season 4. The whole team ended up taking on fixed roles: Egon was "The Brain", Ray was "The Hands", Peter was "The Mouth" and Winston was "The Driver" (which many of the writers noted the UnfortunateImplications of). This was enough to make Straczynski leave his position after Season 3 (though he wrote some later scripts for the show as a free-lance writer).
** The only reason the Egon/Janine relationship was never allowed to go anywhere? Creator/HaroldRamis hated the idea, and since the actors had creative control over their characters, it was vetoed. This is why it was totally dropped in ''Film/{{Ghostbusters}} 2'' for a Janine/Louis relationship.
** Q5 had also wanted Straczynski and the other writers to ditch Ray, as they felt he was a pointless character. However, this was one change that was quickly and successfully vetoed.
* HeyItsThatVoice: (Quoth [[http://www.x-entertainment.com/messages/653.html X-Entertainment]]: "If you're new to the show, it'll take awhile for you to stop expecting [[WesternAnimation/GarfieldAndFriends lasagna jokes]] [from Peter, who is voiced by Lorenzo Music in the early half of the show's run].")
** It becomes HilariousInHindsight, because in 2004, a live-action ''Film/{{Garfield}}'' movie would be released. In that film, Garfield is voiced by Creator/BillMurray, who played Peter Venkman in the Ghostbusters movie.
*** Because Bill Murray complained to the producers that his character "sounds like Garfield", they replaced him with Dave Coulier (''Series/FullHouse'''s Uncle Joey).
** Creator/KathSoucie played the post-{{Chickification}} Janine. It was one of her earliest roles.
** The original Janine was voiced by Laura Summer, who would reuse the voice for Patamon from ''Anime/DigimonAdventure''.
** Creator/MauriceLaMarche played Egon (and sounds a lot like [[WesternAnimation/PinkyAndTheBrain The Brain]] would years later).
*** According to TheOtherWiki, initially they wanted Maurice not to do a Harold Ramis impression, but as an impressionist, Maurice felt he couldn't properly play Egon ''without'' following Ramis' example (he won the part anyway with it). He also tried a "Creator/WoodyAllen" approach, but it didn't fit Egon's personality.
** Creator/FrankWelker pulled [[TalkingToHimself double-duty]] as Ray and Slimer.
** The ''Slimer!'' shorts featured Creator/CreeSummer as Chilly Cooper, an ice cream truck driver who befriends Slimer.
** Crowley from "The Halloween Door" was voiced by Michael Rye, better known as [[WesternAnimation/AdventuresOfTheGummiBears Duke Igthorn]].
** In "Ghostworld" Mrs. Spengler was voiced by Rose Marie, better known as [[Series/TheDickVanDykeShow Sally Rogers.]] An earlier appearance near the end of an episode had Creator/MauriceLaMarche voice her for the last few seconds when she sent the guys out on a call.
* TheOtherDarrin: After the syndicated episodes, Dave Coulier replaced Lorenzo Music as Peter and Kath Soucie replaced Laura Summer as Janine. A season later, Arsenio Hall left for his talk show and was replaced by Buster Jones.
** In the second season, whenever the Stay Puft Marshmallow Man appeared, Frank Welker handled any vocal effects. In Season 3's "Sticky Business," John Stocker took over the role. Later in Season 5's "Partners in Slime," Welker again voiced the character for a brief cameo.
* PromotedFanboy: A number of people involved at the start of production were fans of the movie. Creator/MauriceLaMarche is one such example.
* RecycledTheSeries: Of ''Film/{{Ghostbusters}}''. Humorously enough, the show treats TheMovie as a movie version of the series.
* ShowAccuracyToyAccuracy: Strangely, the Creator/{{Kenner}} toy line had very few ghosts who had actually appeared in the show. Exceptions to this were often lacking in accuracy: the 'Slimer' figure was named Green Ghost and looked more like his film counterpart, having been designed and marketed before the show had even come up with his name; and the original Stay Puft figure is about the same height as the 'busters themselves (the latter was eventually reissued as a plushie that was more accurately sized relative to the Ghostbuster figures- not that it would be physically possible to make a toy of the character to scale with the figures what with the character having been about 100' tall, and even today with a 2' tall Mattel foam figure or Diamond Select coin bank, it's still not quite happened). The likenesses of the Ghostbusters themselves also shares a bit with the early demo reel(as described below) which is why the Ray figure is so fat and why Winston's face is off-model.
** Trendmasters would eventually make a toy of Samhain in the Extreme Ghostbusters line... albeit rather off-model to his animated look.
** Mattel did release a series of 9" action figures with much improved likenesses around the year 2010, although it only saw 6 toys, but it did feature a proper Samhain, FINALLY. Art Asylum also released a line of Minimates that tied in with both the film and cartoon which featured a few ghosts in toy form for the first time.
* TakeThat: Dr. Basingame, a [[ConMan charlatan spiritualist]] first appearing in "The Spirit of Aunt Lois", wore a safari jacket and camera around his neck in that episode - an awful lot like the wardrobe of Jake Kong from ''WesternAnimation/FilmationsGhostbusters''. This was deliberate; WordOfGod said Basingame was a deliberate swipe against the [[DuelingShows rival show]]. On that note, another episode had a brief insult aimed at He-Man, which was animated by Filmation as well.
** A later episode was dedicated at jabbing at the Teenage Mutant Ninja Turtles with 3 rude ghosts that ate pizza- the Turtles own cartoon was trashing Ghostbusters in the ratings at the time.
* TalkingToHimself: Creator/FrankWelker (Ray, Slimer, sometimes also voices ghosts -- he's a ManOfAThousandVoices) and Creator/MauriceLaMarche (Egon, and the Umpire in "Night Game").
* TechnologyMarchesOn: Thanks to the corporate espionage perpetrated by [[CorruptCorporateExecutive Paul Smart]], a super-advanced, AI-driven Robo-Buster X1 was set to put the "dinosaur" Ghostbusters out of business. At its unveiling, the robot revealed it had an incredible 20MB of on-board memory.
* WhatCouldHaveBeen: Creator/{{Filmation}} was in talks to animate this series. If they had, at the very least, [[WesternAnimation/FilmationsGhostbusters their show]] never would've happened.
** Creator/ErnieHudson (Winston in the movies) auditioned for his own character.
** In light of falling ratings after the Slimer ReTool, producers asked JMS to return as head writer for Season 6. JMS had other projects at the time, though he agreed to write a few episodes (chief among them "Janine, You've Changed").
** The executives softened Janine's character to be more "motherly" but they also wanted to make her a full-fledged Ghostbuster as opposed to just a secretary who only occasionally got involved with the plot. Quite a few fans think this might have actually been a good idea.
** An early four minute [[https://www.youtube.com/watch?v=XN5V2c1nN6s demo reel]] featured an entirely different character design for Peter Venkman (one that came closer to the more blue collar looks of live action Venkman BillMurray than the chiseled pretty boy design they ultimately went with), the Ghostbusters wearing their beige movie jumpsuits instead of the multi-color coded jumpsuits they wore in the finished series, and Slimer still appeared to be an antagonist rather than a team pet and mascot.
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