It's no secret that the Big Show has "acromegaly", the same condition that Wrestling/AndreTheGiant suffered from. This is the reason for The Big Show's huge size. Unlike Andre however, he actually got treated for it.
* PromotedFanboy: Show was a [[JustForPun huge]] ProfessionalWrestling fan in his youth. His favorite wrestler was Wrestling/ArnAnderson. He stated that he would like Anderson to induct him into the Hall of Fame some day.