* ActorAllusion: As Warren, Jack Burns would occasionally use his stand up trademark of making a statement to another character then saying "huh?" "huh?" "huh?" until the other character shouts an agreement with him to get him to shut up.
* TheCastShowoff: Andy's singing was showcased in several episodes, as was Jim Nabors'.
* TheDanza: Andy Griffith as Andy Taylor and Elinor Donahue as Ellie Walker
* HeyItsThatGuy: [[http://en.wikipedia.org/wiki/List_of_The_Andy_Griffith_Show_guest_stars Lot of guest stars]], including:
** [[Series/GreenAcres Fred Ziffel]] is a hobo Barney chases away from loitering on the railroad tracks.
** [[Series/GreenAcres From the same universe]], Mr. Drucker is the town drunk in Mt. Pilot, whom Otis befriends when he "runs away". In fact, actor Frank Cady was originally tested for the part of Otis himself, but was determined to not be right for the role.
** [[Series/TheBeverlyHillbillies Also from the same universe]], Jed Clampett is another hobo whom Obie befriends, but turns out to be a bad influence.
** [[Series/PetticoatJunction And again from the same universe]], Uncle Joe is a wandering (and swindling) handiman whom Aunt Bea strikes up something of a brief romance with.
** [[Series/GilligansIsland Gilligan]] was Dud Walsh in one episode, and one episode only (where Charlene wanted a divorce, because she caught him peeping at another girl during church).
** [[Series/ILoveLucy Little Ricky]] is one of Opie's pals.
** [[Series/HogansHeroes Carter]] (no, not ''[[Series/GomerPyleUSMC that]]'' [[Series/GomerPyleUSMC Carter]]) got into a fight with Goober over Goober apparently not fixing the strange noise in the engine of his car.
** [[Series/TheDukesOfHazzard Sheriff Rosco P. Coltrane]] is a guitar player who Andy fixes up for a successful audition with Bobby Fleet and His Band with a Beat.
** Howard Morris directed eight episodes. Morris is best known for voicing Gopher in ''Disney/TheManyAdventuresOfWinnieThePooh'' and Wade Duck on ''WesternAnimation/GarfieldAndFriends''.
** Gene Reynolds directed three episodes. Reynolds is best known as co-creator and co-executive producer of ''Series/LouGrant''.
** Theodore J. Flicker also directed three episodes. Flicker is best known for co-creating ''Series/BarneyMiller''.
** Aaron Ruben directed two episodes, wrote seven episodes, and served as a producer. Ruben served as creator and executive producer of ''Series/GomerPyleUSMC''.
** Sam Bobrick wrote 19 episodes. Bobrick is best known for creating ''Series/SavedByTheBell''.
** Arnold Margolin wrote five episodes. Margolin is best known as co-composer and lyricist for the theme song to ''Series/LoveAmericanStyle''.
** Howard Merrill wrote two episodes. Merrill is best known for co-creating ''Series/IveGotASecret''.
** Earl Barret also wrote two episodes. Barret is best known as co-developer and co-executive producer of ''Series/TooCloseForComfort''.
** Creator/JamesLBrooks also wrote two episodes.
** Paul Henning wrote an episode. Henning is best known as creator and producer of ''Series/TheBeverlyHillbillies'' and ''Series/PetticoatJunction''.
** Ben Starr also wrote an episode. Starr is best known for co-creating ''Series/SilverSpoons'' and co-developing ''Series/TheFactsOfLife''.
* NamesTheSame: In the episode ''The Bookie Barber'', there is a resident of Mayberry named Creator/EmmaWatson
* TheOtherDarrin:
** Ben Weaver, the department store owner, was played by three different actors over the course of the show.
** Four different actors played Wally, the owner of the filling station.
* ThePeteBest: [=McNear=] took over the role of Floyd after Baldwin's one-time appearance as the character.
* RealitySubtext:
** Griffith is a native Tarheel. Mayberry is a pastiche of Mount Airy, where he grew up. Nearby to Mount Airy is Pilot Mountain, renamed to Mount Pilot for the show.
** Being on the show so endeared the state to Frances Bavier that she moved there (specifically to Siler City) later in life.
** Howard [=McNear=] (Floyd TheBarber) had a severe stroke during the run, and upon returning could not walk or stand on his own. He thereafter was always shown sitting or leaning against an object, and would "walk" across the room off camera. When worsening health required him to leave permanently, Floyd retired and the barbershop became Emmett's Fix-It Shop.
* RealLifeRelative: Rance Howard, Ron Howard's real life father, made four separate guest appearances and wrote an episode.
* RecycledScript:
** At least two different episodes has Barney desperately wanting the big solo in choir - in one such episode, he loses to Gomer, whose singing voice is much more suitable for the solo; in the other, he's over confident that he's got the solo while the rest of the choir try to find a way to get rid of him without hurting his feelings.
** In a more literal sense, as mentioned about, scripts were already written with Barney in them for the beginning of Season Six, but with Don Knotts not returning, Barney was simply replaced with Warren in the scripts.
* WhatCouldHaveBeen: Originally, Andy was supposed to be the comedic lead with Knotts as his straight man (similar to their roles in ''No Time For Sergeants'', but they quickly discovered it was funnier the other way around: "By the second episode, I knew that Don should be funny, and I should play straight."
** Andy Griffith wanted black actors to have prominent roles in the series, but he was barred from this because of the fact that, being the 1960s, many southern stations would have refused to air the show. This resulted in only a very occasional black extra showing up as a background character in very few episodes, with more prominent characters appearing in the spinoff only, and Mayberry didn't get any solid black characters until the RFD sequel/retool series many years later.
* WriteWhatYouKnow / NoCommunitiesWereHarmed: Mayberry is based very heavily on Griffith's home town of Mount Airy, NC (and Mount Airy is ''quite'' [[SweetHomeAlabama proud of it]]).