* BizarroEpisode: Intentional for the first few years. Every seventh episode or so was supposed to be weird.
* ChannelHop: Sort of. The show had already been airing on Creator/CartoonNetwork's late night slot for years, and when [[Creator/AdultSwim [adult swim] ]]was made in 2001 to take over Cartoon Network's late night, they just didn't move it as it fit [adult swim]'s demographics. So it wasn't the show that moved, it was the ''channel'' that moved.
* CreatorCameo: To an extent. C. Martin Croker, in addition to voicing both Zorak and Moltar, also animated most of the new animation sequences that appear in the series.
* TheDanza: Andy Merrill as Commander Andy.
* IAmNotSpock: Joel Hodgson is not pleased with Space Ghost confusing him with his character 'Joel Robinson'.
* InMemoriam: "Sharrock," a tribute to musician Sonny Sharrock.
* KeepCirculatingTheTapes: In addition to the final six episodes, three episodes never made it onto DVD at all: "Self Help", "The Mask" (and its companion piece "Le Livre d'Histoire"), and "Gum, Disease". Also "A Space Ghost Christmas", which was never released to DVD in its entirety. Only two songs from the special made it. Also, the unedited versions of:
** "The World Premiere Toon-In" (aka "President's Day Nightmare"): For copyright reasons, all the cartoons featured on the show were cut for the DVD release. Only the wraparounds are shown.
** "Sleeper": A brief scene after the credits with Space Ghost, Zorak and Moltar in the commissary having ditched Slash on the set was removed.
** "Explode": An announcement at the very end of episode from the late BBC DJ JohnPeel, stating that the Ghost Planet will now explode (hence the title of the episode...) was removed.
** "$20.01": The ''Series/UltraSeven'' footage that Joel Hodgson and Space Ghost mock was removed from the DVD and replaced with [[StockFootage non-copyrighted footage]].
** "Glen Campbell": The audio from ''TheSimpsons'' clip at the beginning was removed, along with a line from Space Ghost ("Which one is Homer again? The baby?"), and an additional audio clip of Mr. Burns after the credits.
** "Hipster": Sam Butera sings a portion of "Just a Gigolo", which was cut from the DVD and replaced with an original song.
** "Joshua": William, The King of Imagination's brief appearance was cut for the DVD. Rumor is because Williams Street couldn't track him down to get him to allow his likeness to appear on home video.
** "Cahill": Garrett Morris sings a portion of "For the Love of Money", which was cut from the DVD.
** "Chambraigne": Al Roker was originally part of the Chambraigne commercial. He was replaced on the [=DVDs=] by George Lowe (though some would argue that was an improvement because... it's George freaking Lowe)
** For a time, the unedited versions of the above (as well as the episodes not on DVD) could be obtained through the Adult Swim's "Create Your Custom DVD!" feature, but now that the Adult Swim Store has shut down, the only legal option is to buy the episodes via iTunes.
** Speaking of the Adult Swim store shutting down, for a time it was impossible (aside from buying used copies online for outrageously inflated prices) to obtain Volumes 4 and 5, since they were Adult Swim Store exclusives. However, they have since been made available on iTunes with the rest of the series.
** You can find the episode "The Mask" on the VHS release of that movie, which it was originally made for; it follows the film. (Or, you can just watch it on YouTube.)
* MissingEpisode: ''Copa Toon", a series of specials done for Latin American audiences during the [[TheWorldCup 2002 FIFA World Cup]] and the 2003 Copa America where Space Ghost interviewed several sports personalities were considered lost for more than a decade until the episodes were uploaded to YouTube in 2015. The episodes were unique because they were recorded in both English (with the original cast) and Spanish, yet the interviewee's lines remained in Spanish in both dubs.
** There's also at least 12 missing episodes from the Gametap iteration.
* NamesTheSame: Seasons 3 and 4 each have an episode named "Switcheroo". Both have different premises.
* OldShame: To Mike Lazzo, who considers the show to be dead to him.
* TheOtherDarrin: A variation: Gary Owens, the voice of WesternAnimation/SpaceGhost in the original 1960s cartoon, is used by the current Space Ghost's former mentor, Warren, as a replicant so he could have Space Ghost on his own show. Gary is rendered as an image of Space Ghost over a boiling cauldron that occasionally blinks into his real face. The real Space Ghost, feeling that Warren violated their trust as mentor and student, confronts him and Gary to reclaim his identity.
** In "Spanish Translation", Brak was voiced by C. Martin Croker. In all other appearances, he was voiced by Andy Merrill.
** In "Woody Allen's Fall Project", Space Ghost was played by Andy Merrill, Zorak was played by Dave Willis, and Moltar was played by Gus Jordan.
* TalkingToHimself: C. Martin Croker voices Zorak and Moltar (though his voice was pitched down electronically for Moltar's lines).
* ThrowItIn: Between takes, George Lowe was complaining about how some fruit baskets he bought around Christmas time were recieved by people at Creator/CartoonNetwork. When putting the show together, they decided to use this bit during the intro for ''Fire Drill''.
* TrollingCreator: There's no way the uncut version of "Fire Ant" (that is, Space Ghost crawling after an ant for 10 minutes) could be seen as anything but this.
* WhatCouldHaveBeen: As it was created as a BackdoorPilot (but broadcast after the series' launch), the episode "Baffler Meal" features outdated, preliminary versions of the WesternAnimation/AquaTeenHungerForce just 'cause.
** It also shows us a new future of rock 'n' roll dominated by Colonial-era musicians, who perform a bizarre cover of "[[Music/LedZeppelin Black Dog]]" with fast-food-related lyrics.
** While it was in pre-production, [[Series/FantasyIsland Hervé]] [[Film/TheManWithTheGoldenGun Villechaize]] was in negotiations to co-star as a sidekick of Space Ghost. Sadly, he killed himself before anything happened.
** Certain bits of dialog in the initial draft of "Fire Ant" (as shown in "Table Read") were excised from the completed version, such as the flashback with Dr. Fishopolis; a different flashback to the old Space Ghost show; and a different opening line by Space Ghost: "Sorry I'm late. I was out saving your life... in the future!"
** During Dragon*Con '99, it was revealed that WesternAnimation/TheTick was going to be a guest, but the fact that they couldn't find any good animation to use for the interview left the interview unmade.
** There are two episodes that were announced that were never made, namely "One Way Out", and "Drop Out". One Way Out was going to feature Creator/SethMacFarlane and Creator/SethGreen, but it was never made. Part of the Green interview was used for the beginning of an WesternAnimation/AquaTeenHungerForce episode.
** "Snatch" began life as a completely different episode, "Dinner With Steven". It was featured on the 1998 season DVD as a bonus.
* WriterRevolt: "Joshua" was the last episode written for the 1997 season, which was the longest season of the show. By this time, the writers were exhausted, so they didn't even bother to come up with a plot or do traditional interviews, and instead opted to write a series of sketches, with the motif tying it all together being a paid program starring Space Ghost. Despite their cranky mood (or perhaps because of it), "Joshua" ended up being one of the funniest episodes of the series, thanks to its SomethingCompletelyDifferent style, mixed with quite a bit of SelfDeprecation and DeconstructiveParody.