The following are {{Trivia}}l facts relating to Creator/SethMacFarlane.
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* AdoredByTheNetwork: Ever since ''WesternAnimation/KingOfTheHill'' ended after 12 years on the air and ''WesternAnimation/SitDownShutUp'' flopped so badly that it was canceled after four episodes (along with other animated shows that got the shaft after a short run, like ''WesternAnimaiotn/AllenGregory''[[note]]even though viewer and critic opinion of the show is that it sucks and should not have been made[[/note]] and an animated version of ''WesternAnimation/NapoleonDynamite'' [[WereStillRelevantDammit that came five years too late]]), the Sunday night "Animation Domination" line-up is mostly made up of Creator/SethMacFarlane's cartoons (even with ''WesternAnimation/TheClevelandShow'' canceled, there's still ''WesternAnimation/FamilyGuy'' and ''WesternAnimation/AmericanDad'', though as of the 2014-2015 season, ''Family Guy'' is going to be the only one left because ''American Dad'' is moving to Creator/{{TBS}}.). Currently, the only cartoons that aren't created by Creator/SethMacFarlane on the "Animation Domination" line-up are ''WesternAnimation/TheSimpsons'' and ''WesternAnimation/BobsBurgers''.
* RealLifeRelative: His sister, [[Creator/RachaelMacFarlane Rachael]], also does voice-acting on his shows (the voice of Hayley on ''American Dad'' and regularly contributes additional voices to the other shows).
* ScrewedByTheNetwork: ''Family Guy'' was subjected to this back in the late 1990s/early 2000s. ''WesternAnimation/AmericanDad'' has been this way as well, especially ever since ''Family Guy'' was UnCancelled (''Family Guy'' even has jokes about ''WesternAnimation/AmericanDad'' being nigh-unknown, such as Peter referring to the show as "...whatever FOX is limping to the barn with," and in ''WesternAnimation/AmericanDad'', Brian Griffin stares at Stan and scoffs, "Do I know you?"). Amazingly, ''TheClevelandShow'' wasn't subjected to this treatment, despite the fact that most SethMacFarlane fans don't care much for this show -- at least not until April 2013, when FOX announced that they weren't going to continue with ''The Cleveland Show'' due to low ratings and the popularity of ''BobsBurgers''.
* [[MarthDebutedInSmashBros Seth MacFarlane Debuted in Ted In Japan]]: His film ''Film/{{Ted}}'' is the first time that anything created by him has been shown in Japan, since none of his famous shows are broadcasted there.
* TalkingToHimself:
** Played straight in ''FamilyGuy'' and ''WesternAnimation/AmericanDad'', where Seth voices the father of the family (Peter Griffin and Stan Smith), the bizarre live-in guest (Brian the talking dog and Roger the alien), the next door neighbor with a sexual side (Quagmire the sex addict and Greg Corbin, a male homosexual in a committed relationship), and a news caster (Tom Tucker and, again, Greg Corbin).
** Downplayed and subverted with ''TheClevelandShow'': [=MacFarlane=] only played two characters on the show (Tim the Bear and Dr. Fist), who were later replaced with other actors (Creator/JessHarnell played Tim the Bear during the show's final episodes and Dr. Fist was voiced by TomKenny in one episode and Bryan Cranston in the show's last episodes).
** Parodied and deconstructed on his ''SaturdayNightLive'' monologue where he states that the many vocal impressions he does are in his head all the time and a possible sign of mental illness.
* WhatCouldHaveBeen: Originally, [=MacFarlane=] was hired to do cartoon shorts for the Creator/{{FOX}} sketch show, ''Series/{{MADtv}}'', but backed out in favor of doing his own series. Had he chosen to do work for ''Series/{{MADtv}}'', he would have been just like Creator/MattGroening and created ''Family Guy'' as filler for a sketch show, just like Groening did with ''WesternAnimation/TheSimpsons'' for ''The Tracy Ullman Show''.
** Also, originally: ''The Simpsons'' was going to be canceled after 23 years and Seth's revival of ''WesternAnimation/TheFlintstones'' was going to take its place. This fell through when [=MacFarlane=] decided to put his ''Flintstones'' revival on hiatus and ''TheSimpsons'' was renewed for two more seasons in exchange for extensive budget cuts for cast and crew members in order to keep the show afloat.
* WriteWhatYouKnow: One of the main reasons [=MacFarlane=] chose to make ''Family Guy'' a series was the fact that, up until the late 1990s, there was little to no TV shows that took place in the New England states.
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