* ActorAllusion: When Angel gets his mask back, he starts doing HulkHogan's signature taunt.
* FakeRussian: Oleg Kirrlov. There are Russian last names such as "Krylov" or "Kirillov", but not Kirrlov.
** It's probably misspelt.
* TheOtherDarrin: Quite a few voice actors.
** Charles Shaugnessy, who played the Cockney-voiced Boss in VideoGame/SaintsRow2 (Male Voice 3), is replaced by Robin Atkin Downes.
** Female Voice 1 went from Katie Semine to Creator/LauraBailey.
** Eliza Dushku, who played Shaundi, is replaced by Danielle Nicolet.
* ThrowItIn: The rickshaws that inexplicably explode when destroyed during the getaway from the Safeword nightclub was initially just placeholder behaviour until they could be given proper scripting. When that was implemented, a vocal faction of the dev team insisted that the placeholder script was funnier, and they got their way just days before the game went gold.
* WhatCouldHaveBeen: Several examples:
** There was going to be a SpinOff game called ''Saints Row: Money Shot''/''Saints Row: Drive-By'', which would have been about an Ultor assassin named Cypher, which would have taken place between ''Saints Row 2'' and ''The Third'', and would have bridged a few gaps like [[spoiler:closure for Dex, with Cypher assassinating him]]. The game was never made, and ''Money Shot'' was instead released as a standalone clothing and weapons pack (getting ''Money Shot'' would have allowed you to unlock the outfits).
** Originally, you were going to unlock the Syndicate tower as a crib if you chose to spare it, and it's still presented as one. Also, the storyline changed many times during development, leading to many elements being dropped. Shaundi was originally going to get a big piece of CharacterDevelopment and deal with survivor's guilt instead of going all AxCrazy, and Gat was [[spoiler: going to be revealed as alive and well, and in need of rescue.]] That second plot appears in ''Saints Row IV''.
** Averted with the Fart in a Jar. Originally it was to be cut, the developers believing it was too over the top for the game, but word spread of its existence, leading to fan outcry over the cut. It was ultimately re-included as the final upgrade for the flashbang.
** Originally, the gang specialists were going to be included as Homies. There is a TON of recorded dialogue for each of the gang specialists, especially Kirsten, the Decker's cyber-skating, Shock Hammer-wielding specialist.
** Killbane was originally going to use a dirty bomb to destroy Stilwater, giving the player extra incentive to kill him. This was dropped alongside Shaundi's survivor's guilt story arc for being "too dark".
** [[spoiler: The Kill Killbane ending was supposed to be the original Canonical Ending for the game. The Expansion Pack, "Enter The Dominatrix" would've continued the storyline based on the idea that The Boss let Shaundi and Viola die in order to kill Killbane.]]
*** Despite the presumed implication of the ending, Enter the Dominatrix was to have [[spoiler:Shaundi alive even though the bomb went off]], and the internal names of some audio logs indicate they were originally meant for [[spoiler:Viola, even though she too was supposed to be dead]].
*** Trailers and advertisements for the game showed Philippe Loren as a much younger man and painted him up to be the final boss of the game as well as the mastermind behind the entire syndicate. In the actual game he is an old man who [[spoiler: while fairly badass in the short time he appears in, gets killed off early in the game and replaced with Killbane. He doesn't even get a proper boss battle.]]
*** Originally, Viola and Kiki were supposed to be Japanese twins named Natsuko and Yukako (nicknamed Suki and Yuki) who ran an all-female gang made up of heavily armed former prostitutes to counter the original all-male Morning Star with Philipe and his well-dressed henchmen. However, midway through development the plan was scrapped, both gangs fused together to streamline the story, and Viola and Kiki were made Caucasian to avoid the whole "badass Asian chicks that are subservient to an older man" stereotype. This explains why Morning Star has the most variations of grunts (8), why it is the only gang with male and female grunts (the only females in any other gang are the Deckers' specialists) and the extremely stripperiffic outfits of the female grunts compared to the males' more formal attire.