* EnforcedMethodActing: Creator/DenzelWashington was actually waterboarded during the filming of some of the torture scene, though only for a few seconds per take.
* FollowTheLeader: Stylistically and narratively, this film is very similar to ''Film/TheBourneSeries''.
* SimilarlyNamedWorks: Besides the [[Series/SafeHouse ITV series]], it also shares its name (and a few plot points) with a 1998 made-for-TV movie starring Creator/PatrickStewart.
* WhatCouldHaveBeen:
** The movie was originally set in the favelas of Rio de Janeiro, but the production decided not to shoot there, due to security concerns.
** Creator/ZacEfron, Creator/AndrewGarfield, Creator/JakeGyllenhaal, Creator/TomHardy, Creator/ChrisHemsworth, Creator/GarrettHedlund, Creator/TaylorKitsch, Creator/ShiaLaBeouf, Creator/JamesMcAvoy, Creator/ChrisPine, Creator/ChanningTatum and Creator/SamWorthington were among those considered for the role of Matt Weston.
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