* HeyItsThatVoice:
** Japanese voice actors and actresses:
*** Red is voiced by Creator/JunkoTakeuchi, [[Anime/{{Naruto}} Naruto Uzumaki's]] voice actress.
*** Blue (in Japan, where he's known as Green) is voiced by [[TakuyaEguchi Asemu]] [[Anime/MobileSuitGundamAGE Asuno]].
*** [[Creator/TomokazuSugita Gin]][[Manga/{{Gintama}} -san]], you're the Gym Leader for Pewter City now!?
*** [[Creator/YuiIshikawa Mikasa]] [[Manga/AttackOnTitan Ackerman]] is Mr. Fuji's granddaughter Reina.
*** [[Creator/RikiyaKoyama Yoshikage]] [[VideoGame/JojosBizarreAdventureAllStarBattle Kira]] voices Giovanni.
** The English cast, in a surprising change of pace, is LA-based.
*** Creator/BrycePapenbrook as Red.
*** Creator/LucienDodge as Blue.
*** Creator/KyleHebert as Professor Oak.
*** Creator/JohnnyYongBosch as Brock, well known for playing [[Anime/{{Bleach}} Ichigo Kurosaki]].
*** Creator/CristinaValenzuela as Lass, Red's Nidoran♂, and Cubone.
*** Creator/ChristineMarieCabanos as Reina, Pidgey, and Mew.
*** Creator/LauraPost as Red's Mother and Marowak.
*** Creator/SpikeSpencer and Creator/DougErholtz as Team Rocket members.
*** Creator/KirkThornton as Mr. Fuji and Lance.
*** Creator/JamiesonPrice as Giovanni.
*** Creator/ErinFitzgerald as a Youngster and the Silph Co. Secretary.