* AFIS100YearsSeries:
** AFIS100Years100Movies: #40
** AFIS100Years100Thrills: #4
** AFIS100Years100Movies10ThAnniversaryEdition: #55
** AFIS10Top10:
*** #7, Mystery
* DawsonCasting: Both leads were older than their characters (actually it's not clear how old Roger is supposed to be, given that Cary Grant was in his mid-50s at the time).
* ExecutiveMeddling: The final shot of the film was to be the two leads climbing into be on their train and sharing a passionate kiss with "The End" superimposed over it, but TheHaysCode objected, saying that it implied that the couple were going to have sex (which, let's face it, they probably were) and demanded it be changed. In classic Hitchcock form, he obliged and changed it to [[GettingCrapPastTheRadar their train]] [[FreudWasRight going into a tunnel]].
* HeyItsThatGuy: The Professor is [[Series/TheManFromUNCLE Alexander Waverly]]. Leonard is [[Series/MissionImpossible Rollin Hand]]. Roger's lawyer is [[Series/GetSmart The Chief of CONTROL]]. One of the cops accompanying Roger to Lester Townsend's house is [[Film/TwelveAngryMen Juror #6]]. The phony "Mrs. Townsend" is [[Film/SonOfFrankenstein Elsa von Frankenstein]]. The ticket seller who tries to hold Roger up at Grand Central is actually Doc from ''Film/WestSideStory''. Not to mention Eve Kendall is [[Film/SupermanReturns Martha Kent]] and [[WesternAnimation/TheLegendofKorra the older Katara]].
* ImageSource: This film provides the page image for:
** BetterManhandleTheMurderWeapon
** TraitorShot
* ThrowItIn: An unintentional one. When Eve [[spoiler: shoots Roger in the restaurant with the blanks]], a child actor covers his ears before the gunshot happens. The take was still used, since aside from this, it was the best take.
* WhatCouldHaveBeen:
** As has often been noted, this is perhaps the closest we got to Hitchcock doing a Franchise/JamesBond film.
** Legend has it that Hitchcock denied Creator/JimmyStewart the part of Thornhill because he thought he was too old for it... so instead he got Cary Grant, who was even older than Stewart. (Another theory is that the less-than-spectacular box office results for ''Film/{{Vertigo}}'' caused a falling-out between Hitchcock and Stewart, hence no ''North by Northwest'' for the latter. )
** MGM wanted Cyd Charisse to play Eve Kendall (since she was under contract to the studio) and Cary Grant pushed for Creator/SophiaLoren (whom he'd reportedly fallen for while working with her on ''Houseboat'') before Hitchcock settled on Eva Marie Saint.
** While the film was still in the early scripting stage, a scene taking place at an assembly line in Detroit was envisioned, where the camera would follow two men as they talked while a car was built behind them piece by piece... and at the end, one of the characters would open a door of the now-finished car and a corpse would fall out!
** Hitch himself noted that he wanted the climax to involve the heroes interacting with the faces on Mt. Rushmore, rather than just climbing ''around'' them. Specifically, he wanted Cary Grant to hide for a moment in one of the noses...[[CrowningMomentOfFunny and then have a sneezing fit.]] Alas the government didn't want to risk defacing the monument.
* WordOfGay: Martin Landau stated in interviews that he portrayed Vandamm's henchman Leonard as a closeted homosexual who was secretly jealous of Eve Kendall's relationship with his employer. In the scene where he revealed to Vandamm that Eve was secretly working for the Feds, he commented, "Call it my woman's intuition, if you will..."
* WorkingTitle: ''The Man in Lincoln's Nose''.