* ActorAllusion: Creator/IoanGruffudd who is fondly remembered as sailor Hornblower from ''Series/HoratioHornblower'' miniseries guest-starred in "Truth or Consequences". When Hooten fried him on stage, he refers to him several times as the Captain of his ship.
** Canadian actress Jennifer Finnegan as Dr. Tina Ridgeway
** Subverted with British actor Creator/JamieBamber as Dr. Tyler Wilson, who has US citizenship despite being born in London, thanks to his father being an American.
* RealLifeRelative: Jennifer Finnigan (Dr. Tina Ridgeway) is married to Jonathan Silverman (Dr. John Lieberman).
* ScrewedByTheNetwork: Opinions vary whether the marketing and promotion was good enough. Ratings were lower than expected, and the network opted not to renew it. However, few series gain a big audience or devoted following right from the scratch. Lots of MedicalDrama geeks were intrigued and lots of people watched the show for the stellar cast or Creator/DavidEKelley's reputation. It's sad that this was not enough to merit a new season.
* SendingStuffToSaveTheShow: One fan suggested sending syringes ''en mass'' to the network to show that the series is well-loved.