* TheCastShowoff: Katy Mixon has a beautiful singing voice and puts it to good use often.
* FakeNationality: The character Samuel, a Senegalese immigrant, is played by Nyambi Nyambi, who is a Nigerian-American.
* NamesTheSame: Mike's partner has the first name of [[Series/FamilyMatters another Chicago-area cop]].
** Made all the more humorous when you see that the very same actor has made a string of guest appearances on the show and was the one who marries Mike and Molly.
* ScrewedByTheNetwork: Despite being a moderate success in the ratings (not as big as Creator/ChuckLorre's''Series/TheBigBangTheory'' or ''Series/TwoAndAHalfMen'', but still steady), CBS pulled the plug with a shortened sixth season and never even told the cast. Creator/MelissaMcCarthy found out about it through a statement co-star Rondi Reed made to the press.
* StarMakingRole: Was this along with ''Film/{{Bridesmaids}}'' for Creator/MelissaMcCarthy.
* TooSoon: The 3rd season finale was going to air on Monday 5/20/13 but was pulled rather quickly due to how it was going to be about how Chicago was hit by a Tornado. However due to the fact Oklahoma was substantially damaged by a Tornado recently CBS decided to pull the 3rd Season finale out and replaced it with a rerun. The finale eventually aired Thursday 5/29/13.

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