* ActorAllusion: In one episode Pleakley claims he and Jumba are "Canadians from Canadia." Kevin [=MacDonald=] is Canadian.
* CrossDressingVoice: Creator/TressMacNeille, Creator/TaraStrong, Dionne Quan, Creator/NancyCartwright and FrankWelker for several experiments.
** ''TheKidsInTheHall'' cast members Scott Thompson and Bruce [=McCulloch=] voice Pleakly’s mother and sister Pixley, respectively.
* ExecutiveMeddling:
** Producers hated Angel and didn't want her to appear again. After finding out about her popularity among fans, they relented.
** On the other hand, Kioni Jameson was mandated by Disney execs as an audience avatar, and the writers hated him for it.
** The show was originally conceived as an action-adventure series with a similarly sombre tone as the film, but DisneyChannel wanted something LighterAndSofter.
* HeyItsThatVoice: Nosy (Experiment 199) is [[Disney/{{Hercules}} Pain]], one of [[WesternAnimation/HouseOfMouse Hades]]’s shape-shifting minions.
** [[Literature/MaxAndRuby Ruby the Rabbit]] is Shush (Experiment 234).
** Thresher (Experiment 544) was [[WesternAnimation/ThePowerpuffGirls the Mayor of Townsville]].
** [[WesternAnimation/{{Rugrats}} Kimi]] [[WesternAnimation/AllGrownUp Finster]] is [[CrossDressingVoice Heat]] (Experiment 609).
*** Friends [[WesternAnimation/{{Rugrats}} Tommy]] [[WesternAnimation/AllGrownUp Pickles]] and [[WesternAnimation/{{Rugrats}} Phil]] [[WesternAnimation/AllGrownUp DeVille]] are the [[CryingLittleKid crying kid]] in the purple Crayola crayon costume and the {{bed sheet ghost}} trick-or-treater in “''[[HalloweenEpisode Spooky]]''.”
** (Experiment 150) Clyde’s [[Series/ArrestedDevelopment James Buck]].
** [[Series/ShitMyDadSays Will]] [[Series/{{MADtv}} Sasso]] is Heckler (Experiment 322).
** FrankWelker does [[CrossDressingVoice Gigi]] (007) [barking], Backhoe (040), Zawp (077), Shoe (113), Weasel (148), Nosox (204), Sparky (221), Butter (227), Link (251), Spooky (300), Nodessertro (340), Slimy (390), Huggo (489), Ploot (505), Deforester (515), Digger (529), Tank (586), Sinker (602), Slugger (608), Plasmoid (617), Stitch (626) [growling vocals], Doubledip (002), Poki (036), Fudgy (054), Stamen (103), Shredder (134), Evile (627) [growling vocal], Jam (202), Pix (214), Glitch (223), Kingpin (229), Snooty (277), Spike (319), Swirly (383), Choppers (441), Yang (502), Sprout (509), Slushy (523), Blake (583), Kixx (601), Holio (606), Blandzilla (612), Chopsuey (621), Shrink (001), Checkers (029), Hocker (051), Clink (086), Bugby (128), Finder (158), Retro (210), Poxy (222), Mashy (225), Mr. Stenchy (254), Morpholomew (316), Swapper (355), Spats (397), Leroy [growling vocal], [[CrossDressingVoice Yin]] (501), Woody (507), Splat (519), Blowhard (533), Icecrusher (595), Zap (603), El Fin (611) and Splodydead (619).
** TressMacNeille does [[CrossDressingVoice Felix]] (010), Carmen (123), Clip (177), [[CrossDressingVoice Melty]], (228), [[CrossDressingVoice Amnesio]] (303), [[CrossDressingVoice Drowsy]] (360), [[CrossDressingVoice Richter]] (513), Phoon (540), Gigi (007) [voice], [[CrossDressingVoice Topper]] (025), Bonnie (149), Millie (220), Tickle-Tummy (275), [[CrossDressingVoice Hunkahunka]] (323), Mary (455) and [[CrossDressingVoice Cannonball]] (520).
** JeffBennett does Fibber (032), PJ (133), Slick (020), Yaarp (613), Elastico (345), Kernel (014), Skip (089), Woops (600), Derrick (566), Hammerface (033), Sample (258), Wrapper (521), Ace (262), Gotchu (031), Stopgo (102) and Remmy (276).
** RobPaulsen does Houdini (604), Frenchfry (062), Lax (285), Wishy-Washy (267), Forehead (044), Manners (358), Squeak (110), Boomer (288) and Reuben (625).
** TaraStrong does [[CrossDressingVoice Babyfier]] (151), Angel (624), Crystallene (618), Belle (248), Precious (400) and [[CrossDressingVoice Dupe]] (344).
** Chris Sanders does Leroy, Evile (627) and Stitch (626).
** NancyCartwright does [[CrossDressingVoice Shortstuff]] (297), [[CrossDressingVoice Launch]] (607) and [[CrossDressingVoice Phantasmo]] (375).
** GreyDeLisle does Sproing (249) and Vailet (030).
** Victoria was voiced by [[Series/BigLove Rhonda Volmer]] in her first appearance and [[TheOtherDarrin then]] by [[WesternAnimation/PhineasAndFerb Isabella Garcia-Shapiro]] / [[WesternAnimation/YoungJustice Barbra Gordon]] in her second.
** Mertle’s mother is the [[Creator/AprilWinchell daughter]] of Creator/PaulWinchell ([[WesternAnimation/WackyRaces Dick]] [[WesternAnimation/DastardlyAndMuttleyInTheirFlyingMachines Dastardly]]/[[WesternAnimation/TheSmurfs Gargamel]]).
** [[WesternAnimation/TeachersPet Leonard Amadeus Helperman]] is Lilo’s crush Keoni Jameson and his father and Nani’s boss is [[Series/{{Seinfeld}} Tim Whatley]] who’s married to [[Series/MalcolmInTheMiddle Lois]] and has six sons with her.
** In his debut episode, Yang melts [[WesternAnimation/{{Futurama}} Philip J. Fry]]’s car after the latter aggravates the [[MagmaMan former]] by honking and yelling at him.
** When not kicking butt as either the [[WesternAnimation/BatmanBeyond second Batman]] or the [[WesternAnimation/BatmanTheBraveAndTheBold third Blue Beetle]] and [[WesternAnimation/TheSecretSaturdays dealing with crpytids]] alongside his long lost sister, [[Series/BoyMeetsWorld Corey Matthews]]’ older brother [[WesternAnimation/KimPossible Ron Stoppable]] works as a waiter if not manager at [[SuckECheeses Macki Macaw’s]] restaurant.
** [[WesternAnimation/AlvinAndTheChipmunksMeetTheWolfman Madame Raya]] is Mertle’s aunt.
** Swedish Stitch is DonaldDuck.
** Mertle is voiced by Liliana Mumy, the daughter of child actor Bill Mumy, whom most original ''TwilightZone'' fans might remember from the episode "It's A Good Life"[[note]]Bill Mumy was Anthony, the child who had omnipotent powers and forced everyone in his town to be happy or incur his wrath, usually by being sent to a dimension called "the cornfield". An episode of the 2003 revival had an episode that revisited Anthony, who is now the father of a daughter who has his powers, with the daughter played by Liliana[[/note]] and the voice of Panini (the bunny girl who's obsessed with Chowder) on the CartoonNetwork show ''{{Chowder}}''.
* MissingEpisode: The {{crossover}} episode with ''{{WesternAnimation/Recess}}'' never aired on Disney Channel, possibly because the network was worried that the kids that were into ''Lilo and Stitch'' would have no idea what ''Recess'' is.
* TalkingToHimself: [[AllStarCast Hoo-boy]]! Just take a look at Creator/JeffBennett, Creator/NancyCartwright, Music/GreyDeLisle, Creator/TressMacNeille, Creator/RobPaulsen, Chris Sanders, TaraStrong and Creator/FrankWelker above!
** Lilo and Victoria, though only in the latter’s first appearance.
** Both Mrs. Edmonds and Aunt Stacey are voiced by Creator/AprilWinchell.
* TheOtherDarrin:
** In one episode, Creator/KevinMichaelRichardson voiced Cobra Bubbles, though Ving Rhames does voice the character though it’s unknown which episodes.
** Creator/DeeBradleyBaker replaced Jason Scott Lee as the voice of David in the TV series.
** In her first appearance, Victoria is voiced by Daviegh Chase, which lead to TalkingToHerself with Lilo, and in her second appearance, Alyson Stoner voiced her.
* WhatCouldHaveBeen: Precious (Experiment 400) was meant to have her own episode as a parody of ''Literature/TheLordOfTheRings'' where she would be thrown into an [[ChekhovsVolcano active volcano]] where the extreme heat from the lava would defeat her but alas, the idea was scrapped do to copyrights . . . now why they couldn’t use [[MagmaMan Yang]] for a [[FridgeBrilliance lava source]] is beyond anybody’s guess.
----