** Creator/FredTatasciore is the Hulk again and Bryce Johnson ([[DoctorStrangeTheSorcererSupreme Doctor Strange]]) is Bruce Banner.
** Creator/SteveBlum is Wolverine again.
** Matthew Wolf ([[VideoGame/KingdomsOfAmalurReckoning King Wencen]]) is Thor for the [[ThorTalesOfAsgard first time]].
** Creator/TomKane is Professor Thornton for the [[WesternAnimation/WolverineAndTheXMen first]] [[WesternAnimation/AvengersEarthsMightiestHeroes time]].
** Creator/NolanNorth is Deadpool [[VideoGame/SpiderManShatteredDimensions for the]] [[VideoGame/MarvelVSCapcom3 first time]].
** Creator/NicoleOliver is Betty Ross ([[WesternAnimation/NextAvengersHeroesOfTomorrow again]]) and Valkyrie.
** Mark Acheson ([[Anime/TransformersArmada Unicron]], [[Manga/BlackLagoon Boris]]) is Sabertooth.
** Creator/JanyseJaud is Lady Deathstrike and Hela.
** Colin Murdock ([[WesternAnimation/BeastWars Quickstrike]]) is Omega Red.
** Graham [=McTavish=] and Creator/KariWahlgren are Loki and Enchantress [[WesternAnimation/AvengersEarthsMightiestHeroes for the first time]].
** Music/GreyDeLisle is Sif.
** Creator/PaulDobson is Hogun.
** Jay Brazeau ([[WesternAnimation/HeManAndTheMastersOfTheUniverse2002 Vormus]]) is Volstagg.
** Jonathan Murdock ([[WesternAnimation/FantasticFourWorldsGreatestHeroes Wizard]]) is Fandral.
** Creator/MichaelAdamthwaite is Balder.
** French Tickner ([[Manga/DeathNote Watari]]) is Odin.
* TheOtherMarty: Deadpool was originally voiced by someone working for The Ocean Group, but the producers didn't feel he worked very well. They then brought in Creator/NolanNorth (who was already working for them in ''WesternAnimation/WolverineAndTheXMen'') and had him improvise lines for Deadpool.
** ThrowItIn: Most of North's dialogue for Deadpool was improvised as a result.