** Porn star Candi Suxxx is voiced by real-life former porn star Jenna Jameson.
** This is not the first time Ray Liotta has [[Film/GoodFellas played an Italian American gangster in a period piece]].
* ColbertBump: An entire generation of gamers became fans of 80's music thanks to this game.
* MoneyDearBoy: Ray Liotta has stated that he did the game purely for the money. Thankfully, he earned his paycheck.
** "Running with the Night" by LionelRichie is only in the original [=PS2=] game, it is cut from every other version.
** Briefly, [[http://www.destructoid.com/gta-vice-city-pulled-digitally-from-steam-other-outlets-238752.phtml the game was pulled from Steam]] and other outlets, as apparently ''Wanna Be Starting Something'' is, all of a sudden, [[JustForPun starting something]]. Everything was worked out and the game's back on Steam, song intact.
** Played straight on the Playstation 3 re-release. Both Michael Jackson songs got removed from the soundtrack. When starting a new game, the player will now hear Self Control by Laura Branigan instead of Billie Jean when they enter a vehicle for the first time.
** For the 10th anniversary release, in addition to the Music/MichaelJackson songs, five other songs were cut. Those songs are "Wow" by Music/KateBush, "Bark at the Moon" by Music/OzzyOsbourne, "Rockit" by Music/HerbieHancock, "Looking for the Perfect Beat" by Afrika Bambaataa and the Soulsonic Force & "The Smurf" by Tyrone Brunson.
* WhatCouldHaveBeen: The actor who voiced Pastor Richards [[AuthorExistenceFailure died]] during development. His character was supposed to have a larger role in the game.
** One unused phone conversation has Avery Carrington sending Tommy on a mission to the "Gator Keys". This hints that a Florida Keys stand-in was planned and may have even seen some development, but was ultimately scrapped.
* WordOfGod: Yes, that was Vic Vance, Lance's older brother and protagonist of ''VideoGame/GrandTheftAutoViceCityStories'' that got gunned down in the opening cut scene.