* AuthorExistenceFailure: Or rather, character designer existence failure. With Clement Sauvé's passing, it makes the show's return from its exec-mandated "hiatus" even less likely.
* HeyItsThatVoice:
** Creator/JasonMarsden is Duke.
** Creator/KharyPayton is Ripcord.
** Creator/CharlieAdler is [[WesternAnimation/GIJoeResolute once again]] Cobra Commander.
** Creator/KevinMichaelRichardson is Roadblock.
** Lee Majors ([[TheSixMillionDollarMan Steve Austin]]) is General Abernathy.
** Creator/ClancyBrown is Destro, using a voice that merges the smooth cruelty of SelfDemonstrating/{{Lex|Luthor}} [[{{DCAU}} Luthor]] with a Scottish accent reminiscent of [[WesternAnimation/SpongebobSquarepants Mr. Krabs]].
** Creator/NikaFutterman is Lady Jaye.
** Creator/BrianBloom is Zartan.
** Creator/MichaelBell and Creator/BJWard, the original voices of Duke and Scarlett, [[RemakeCameo voice Duke's parents]].
** Creator/NolanNorth is Snow Job.
** Creator/CarlosAlazraqui is Shipwreck.
** Creator/TroyBaker is Airtight.
** Keith Ferguson ([[WesternAnimation/AvengersEarthsMightiestHeroes General Ross]], [[KingdomHearts Marluxia]]) is Heavy Duty.
** Danny Cooksey ([[WesternAnimation/XiaolinShowdown Jack Spicer]], [[WesternAnimation/StaticShock Hotstreak]]) is young Snake Eyes.
** DavidKaye is the narrator in the opening and Scarlett's dad.
** Stephen Stanton ([[WesternAnimation/StarWarsTheCloneWars Mas Amedda, Tarkin, Moralo Eval]], [[WesternAnimation/WolverineAndTheXMen Blob]]) is Tomax and Xamot.
** Creator/MichaelEmerson is Dr. Venom.
** Natalia Cigliuti ([[TheGlades Detective Sam Harper]]) is Scarlett.
** Matthew Yang King ([[VideoGame/WarcraftIII Illidan Stormrage]]) is Tunnel Rat.
** Tatyana Yassukovich ([[WesternAnimation/BatmanTheBraveAndTheBold Morgaine le Fay]], [[WesternAnimation/StarWarsCloneWars Barris Offee]]) is Baroness.
** Fred Willard ([[WesternAnimation/TransformersAnimated Swindle]]) is the mayor.
** Creator/LiamOBrien is Red Star.
** Creator/CoreyBurton is Law.
** Creator/PhilLaMarr is Scrap-Iron.
** Andrew Kishino ([[WesternAnimation/TheSpectacularSpiderMan Kenny Kong, Ned Lee]]) is Storm Shadow.
** Charlie Schlatter ([[WesternAnimation/TheBatman The Flash]], [[WesternAnimation/{{Ben 10}} Young!Kevin Levin]]) is Wild Bill and Dr. Mindbender.
** Andre Sogliuzzo ([[WesternAnimation/AvatarTheLastAirbender King Bumi]]) is Major Bludd.
** Greg Ellis ([[WesternAnimation/TeenTitans Malchior]], [[WesternAnimation/TheBatman Count Vertigo]], [[MarvelVsCapcom3 Rocket]] [[WesternAnimation/AvengersEarthsMightiestHeroes Raccoon]]) is Breaker.
** Peter [=MacNicol=] ([[WesternAnimation/TheSpectacularSpiderMan Doctor Octopus]], [[WesternAnimation/JusticeLeagueUnlimited Chronos]], [[WesternAnimation/TheBatman Dr. Kirk Langstrom (Man-Bat)]]) is Firefly.
** Creator/KimMaiGuest is Jinx.
** Creator/ScottMenville is Vince Hauser.
** Creator/KeoneYoung, the original voice of Storm Shadow, is [[RemakeCameo Hard Master]].
** Creator/JenniferHale is Wendy.
** Creator/JamesArnoldTaylor is Russel Clemons.
** Creator/TravisWillingham is Sully.
** Creator/KeithSzarabajka is the warden.
** Danica [=McKellar=] ([[WesternAnimation/YoungJustice Miss Martian]]) is Sister Leia.
** Jerry O'Connell ([[WesternAnimation/JusticeLeague Captain]] [[WesternAnimation/SupermanShazamTheReturnOfBlackAdam Marvel]]) is Barbeque.
** Daniel Dae Kim ([[WesternAnimation/TheLegendOfKorra Hiroshi Sato]]) is Teddy Lee.
* ScrewedByTheNetwork: It was announced that after the first season is finished, the show will be going on hiatus in order to "keep creative continuity with the [[GIJoeRetaliation upcoming live action film]]." To say that this has left the show's future in doubt would be an understatement.
** And in the show's first run, the episodes were ''aired out of order''. For better or for worse, they did this to time the two-part Christmas episode ''Homecoming'' correctly. This required additional shuffling around because Storm Shadow appears in it, so the also-two-part ''Return of the Arashikage'' had to be moved as well to introduce him first. After this, the airing order was correct.
** And the tie-in toyline got screwed by Hasbro as well, being hurriedly inserted in the 30th Anniversary assortments, suffering from loss of equipment to cut costs, show characters Airtight and Law being little more than 30th Anniversary toys shoehorned in to pad out the Renegades stuff and worst of all, the line being cut abruptly before the five main characters could even get a toy release (Roadblock got the shaft). '''Oi.'''
** The movie has been delayed for a year, postponing the series' fate even longer.
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