* EnforcedMethodActing: Sean Connery is truly terrified of spiders. The legs of a stuntman were used when the tarantula crawled onto Bond. Note the shot when the spider is on his shoulder -- it's walking on a pane of glass. Once you've seen it you can't unsee it.
* HeyItsThatGuy: Felix Leiter is Jack Lord of ''Series/HawaiiFiveO'' fame.
* ItWillNeverCatchOn: First, it was ignored by many studios. Then Creator/UnitedArtists [[AndYouThoughtItWouldFail gave little money and attention on the US release]]. 22 movies later...
* NoBudget: United Artists only lent $1 million. The art director got an extra cash from the producers' own pockets, and the special effects people convinced UA to give an extra $100,000 to do the CollapsingLair.
* ThePeteBest: Peter Burton as Q. Desmond Llewellyn would take over the role starting with ''Film/FromRussiaWithLove''.
* SameLanguageDub: Strangways and the photographer are dubbed, and Nikki Van der Zyl dubbed over Eunice Gayson and Ursula Andress...
** NonSingingVoice: ...which also had a singing voice.
* SerendipityWritesThePlot: The idea of Rider being trapped among crabs was scrapped because the crabs that would attack her weren't moving (being flown frozen from the Caribbean didn't help...).
* SimilarlyNamedWorks: The 2007 Systems in Blue song "Dr. No" is not intentionally related to the film, but there's a {{fan vid}} [[VideoFullOfFilmClips using clips from the film]].
* WhatCouldHaveBeen: Bond original line was simply "I am James Bond", but Sean Connery felt it was rather weak and [[BondJamesBond went off script]], resulting in one of the most famous movie lines of all time.
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