* BannedEpisode: The ''What a Cartoon! Show'' pilot episode, "No Smoking" (due to claims of the short glamorizing tobacco use and because the short wasn't part of the actual series) and the series episode "Buffalo Gals" (due to the lesbian innuendo and visual puns). Both aren't even included in Netflix streaming version.
* {{Bowdlerization}} and EditedForSyndication: The episode "Comet" was edited in reruns to change Dad's line from, "Oh, divot!" ([[MondeGreen sounding almost like "Damn it!"]]) after hitting his golf ball and sending it flying to "Oh...two!" Since it started airing on Boomerang in America, the original line has been reinstated. The line is also uncut on the Netflix streaming version.
* CrossDressingVoices: Creator/CharlieAdler as Cow.
** The episode "Cow's Toys" has Creator/TomKenny voice an unnamed little girl (you know it's him because "she" sounds like Heffer Wolfe from ''WesternAnimation/RockosModernLife'' when "she" yells, "Mommy! That stinky bear doll hurt my feelings!").
* EditedForSyndication: In the summer of 1999, CartoonNetwork split ''CowAndChicken'' and ''IAmWeasel'' into separate shows, and thereafter, reruns of both shows were essentially a shuffle of three random segments in a half-hour, with "Buffalo Gals" replaced with "Orthodontic Police" and "Comet!" edited to redub "Oh, divot!" to "Oh...two!" Other episodes, like "Grizzly Beaver Safari" and "Chicken in the Bathroom" were pulled for reasons unknown (some say content; others say the episodes weren't good enough for the syndication package).
* ExecutiveMeddling: After the first season was completed, David Feiss wanted to drop the ''WesternAnimation/IAmWeasel'' segments from the show altogether, but Cartoon Network demanded that he keep it in; eventually, a compromise was reached, that would allow Feiss to have Red Guy cross over into the Weasel segments, as to hold his interest in continuing the segment (and eventually, more characters, including Cow and Chicken themselves, were allowed to cross over into the Weasel segments).
* HeyItsThatVoice - Besides Charlie Adler as Cow and Chicken, Creator/CandiMilo as Mom and the Teacher, and Creator/DeeBradleyBaker as the dad, there's also some other familiar voices:
** Flem is voiced by Howard Morris (Wade the Duck on the "U.S. Acres" [or "Orson's Farm," if you're watching an overseas cut of the show] segment of ''WesternAnimation/GarfieldAndFriends'').
** Earl is voiced by [[WesternAnimation/TheSimpsons Dan Castellaneta]] (using the same drunken voice he uses for Barney Gumble).
** On the episode where Cow babysits Chicken while Mom and Dad go to a comedy club, the crying comedian is voiced by real-life comedian and kids' cartoon writer Steve Marmel (who also wrote episodes for this show, like "Dirty Laundry" and "Perpetual Energy").
** Red's mom was voiced by Phyllis Diller.
** The farmer at the beginning of "Space Cow" is voiced by Creator/WillFerrell.
* KeepCirculatingTheTapes: The first two seasons of the show are available on DVD, but only if you live in Australia (and they're region-locked, so they can't play on just any DVD player). Only "The Cow With Four Eyes" and "Me an' My Dog" were ever released on DVD in the United States as part of special holiday DVD sets.
** Netflix does have the show on streaming, ''but' the way it's set up is weird and inconvenient. Rather than add new episodes to its stream, the season one episodes were soon replaced with season two episodes. [[TheTapeKnewYoudSayThat And, before you ask]], no, the BannedEpisode "Buffalo Gals" was not included (though "Buffalo Gals" is available on online video and torrent sites, so it's not like it's gone forever, but [[ScrewedByTheNetwork it is a screw to the fans that not all of the episodes are included]]). However, the episode "Comet!" is no longer edited to remove "Oh, divot!"
* ScrewedByTheNetwork: Somewhat. Before the final season had finished its initial run, Creator/CartoonNetwork jumped the gun at splitting ''I Am Weasel'' into its own "spinoff". Because of this, the remaining "new episodes" of the series were essentially unaired "Cow and Chicken" segments cobbled together into half hour episodes.
* TalkingToHimself - Much like Creator/BillyWest, Creator/JimCummings, Creator/TressMacNeille, Creator/SethMacFarlane, Creator/CreeSummer, Creator/KathSoucie, and other past and present cartoon voice actors, Charlie Adler voices a large amount of characters (Cow, Chicken, The Red Guy, I.R. Baboon, and some one-shot characters) who all interact with each other in any given episode.
* WorkingTitle: "Comet!" was originally called "Dad's Ball" (and was most likely changed because of the censors).