* ActorAllusion:
** There's quite a few jabs at Creator/WilliamShatner's iconic Captain Kirk role, such as when Denny is given a cellphone by one of his many girlfriends and it makes the ''Franchise/StarTrek'' communicator beeping sound whenever he flips it open.
** Also, when describing a parasitic water bug,
-->'''Alan''': They call them cling-ons.
-->'''Denny''': Did you say ''Klingons''!?
** The third season episode "Son of the Defender" used footage from the 1950's Defender TV movie featuring Shatner to present Denny as a young attorney clashing with his father. It was surprisingly emotional.
** In one episode, Valerie Bertinelli appeared as a guest character, and her appearance was heralded with the theme from ''Series/OneDayAtATime'', the show that made her a star.
* FakeAmerican: Canadian Creator/WilliamShatner as staunch, gun-loving Denny Crane.
* HeyItsThatGuy: Nicknamed the "science fiction retirement home" for featuring [[Series/StarTrekTheOriginalSeries Captain Kirk]], [[Series/StarTrekDeepSpaceNine Odo]] (who clearly prefers working with Sisko), [[Film/{{Stargate}} Daniel Jackson]], [[Film/TwoThousandTenTheYearWeMakeContact SAL 9000]] and [[Series/StarTrekVoyager Seven of Nine]] among others.
** [[UpToEleven Taken even further]] in a third season episode with [[Series/StarTrekDeepSpaceNine Odo]] ''[[Series/StarTrekDeepSpaceNine and]]'' [[Series/StarTrekDeepSpaceNine Quark]], who are described as "old friends," arguing with each other.
** [[Film/BladeRunner Zhora]] appeared as Beverly Bridge, Denny's girlfriend and eventual (for about half an hour) seventh wife.
** Guest starring [[Series/StarTrekVoyager Neelix]]. And the voice of [[WesternAnimation/{{Futurama}} Leela]], if you're in to that kind of thing.
** Looks like MurphyBrown has a successful legal career after broadcasting.
** Now GinaTorres (Zoe on ''Series/{{Firefly}}'') has appeared too.
* IAmNotSpock: For a lot of people, this show was responsible for Creator/WilliamShatner not just being Captain Kirk. In fact inverted, now people make Denny Crane jokes about old ''Series/{{Star Trek|The Original Series}}'' episodes.
* YouMightRememberMeFrom: Creator/CandiceBergen's earlier claim to fame was on the [[LongRunner long-running]] sitcom ''Series/MurphyBrown''.
** And Christian Clemenson played sidekick to Bruce Campbell as another lawyer, Socrates Poole, in ''Series/TheAdventuresOfBriscoCountyJr''.
*** Perhaps more relevantly, Clemenson played Spader's brother in Bad Influence.
**** John Larroquette, who joined the cast as the straight-laced DeadpanSnarker Carl Sack is certainly better known for playing a lawyer, who was the complete opposite on ''NightCourt'', Dan Fielding.