* ActingForTwo:
** William Morgan Sheppard voices both Lawrence Limburger and the Sand Raiders' leader Slobber the Mutt.
** [[Creator/JimCummings1952 Jim Cummings]] voices both Saddle Sore and Deathmaster in "So Life Like" as well as the Plutarkians Gerald Gruyere and Gutama Gouda in "Diet of Worms".
* BannedInChina: While the franchise is not necessarily banned in China, [[https://www.dailymail.co.uk/news/article-7920537/University-Minnesota-student-jailed-China-tweeting-pictures-cartoon-villain.html a University of Minnesota student has gotten into trouble]] for tweeting images of the BigBad of the original cartoon, Lawrence Limburger, as well as Franchise/WinnieThePooh; both characters supposedly bear a resemblance to Chinese president UsefulNotes/XiJinping.
* CelebrityVoiceActor:
** The title character of the episode "Hard Rock" was voiced by television and radio presenter Riki Rachtman.
** Creator/IanZiering, Leah Remini, Creator/LukePerry, Creator/BradGarrett, Creator/BrianAustinGreen, Creator/MarkHamill, Creator/CCHPounder, Creator/DavidWarner, Elinor Donahue (who plays Betty Anderson in the 1950s sitcom ''Series/FatherKnowsBest''), Creator/JessHarnell, and Creator/RussiTaylor (the voice of Minnie Mouse since the '80s up until her passing in 2019) are on ''this'' show as well.
* CrossDressingVoices: Creator/SusanSilo as Dr. Karbunkle, and Leeza Miller-[=McGee=] (Charley Davidson) as Modo's nephew Rimfire. Only once, though.
* GermansLoveDavidHasselhoff: The 1993 series is very popular in Finland, partly due to the Finnish dub adding mild profanity (such as references to sex toys) and references to contemporary real-life people that were not present in the original version.
* InternationalCoProduction: Animation contractor Creator/PhilippineAnimationStudioInc returns from the original series to co produce the 2006 revival.
* KeepCirculatingTheTapes: Only the first season was released on DVD in America, and it is now out of print.
* NoExportForYou: The 2006 revival suffers this in two ways:
** The original show was only released on [=DVD=] in full in France (with the original English dub), once. It sold out quick, and ever since then was never re-released in France, or anywhere for that matter.
** While it finally aired in America on [[Creator/FourKidsEntertainment 4Kids]] in 2008, seven episodes never got a chance to air before the show was pulled from the schedule ("Desperado", "Cat and Mouse", "First Mice on the Moon", "Once Upon a Time on Earth" parts 1-3, and the GrandFinale "Turf Wars").
** DVD releases have only been available in the United Kingdom, Australia, New Zealand, and Bulgaria.
* TheOtherDarrin:
** Napoleon Brie's henchman Number One was originally voiced by Creator/MarkHamill, but was voiced by Creator/JeffBennett during his final appearance in the episode "Hit the Road, Jack".
** Modo's nephew Rimfire was originally voiced by Creator/RobPaulsen in the three-part episode "Back to Mars", with Leeza Miller-[=McGee=] voicing him in a flashback of when he was a child. The remainder of his appearances in the original series had him voiced by Brian Austin-Green, while his appearance in the 2006 revival episode "Break Up" had Creator/JessHarnell voice him.
** Some other cases of characters being recast in the 2006 revival.
*** Creator/LisaZane replaces Leeza Miller-[=McGee=] as Charley Davidson.
*** While Peter Strauss reprises his role as Stoker for five episodes, the rest of the series has him replaced by Creator/JimWard.
*** Dina Sherman replaces Leah Remini as Carbine.
*** Creator/JenniferHale replaces Creator/KathSoucie as Harley.
*** Aside from replacing Brian Austin-Green as Rimfire, Creator/JessHarnell also replaces Creator/BradGarrett as Greasepit, Stu Rosen as the Pit Boss, and Creator/JeffBennett as Lord Camembert.
*** Dr. Catorkian is voiced by Creator/JessHarnell for most of the series, but Creator/JimWard fills in for him in the episode "Manchurian Charley".
*** Cataclysm is usually voiced by Creator/ClancyBrown, but his grunts in "Biker Mice Down Under" and "Once Upon a Time on Earth, Part One: Stoker's Gambit" are provided by Creator/DorianHarewood and he is voiced by James Avery in the LicensedGame for Platform/PlayStation2.
* ProductionPosse: Several actors from ''Series/BeverlyHills90210'' have roles in the series. Ian Ziering (Steve Sanders) plays Vinnie, Luke Perry (Dylan [=McKay=]) voices Napoleon Brie, Brain Austin Green (David Silver) voices Modo's nephew Rimfire, and Jason Priestley (Brandon Walsh) guest-starred in two episodes as Jack [=McCyber=].
* RecycledScript: "[[Trivia/BikerMiceFromMarsS2E32ModoHangsItUp Modo Hangs It Up]]" and the ''WesternAnimation/SWATKats'' episode "Razor's Edge", both written by the same author, share similar plots: one of the heroes suffers a HeroicBSOD followed by a TenMinuteRetirement after the villain tricks him into thinking he injured a civilian.
* RoleReprise: While the revival had most of the supporting characters recast, some of the actors from the original series return to reprise their roles.
** Creator/RobPaulsen, Ian Ziering, and Dorian Harewood all return as Throttle, Vinnie, and Modo.
** William Morgan Sheppard and Susan Silo reprise their roles as Lawrence Limburger and Dr. Karbunkle in the few episodes featuring them.
** Creator/LukePerry returns as Napoleon Brie in "Once Upon a Time on Earth, Part Two".
** Peter Strauss reprises his role as Stoker for five episodes, with Creator/JimWard replacing him for the rest of the series.
* ShortRunInPeru: The revival initially aired from 2006 to 2007 on the British television channel [=CITV=]. The series did eventually air in America on [[Creator/FourKidsEntertainment 4Kids]] in 2008, but was pulled from the schedule before every episode had a chance to air. While the revival was said to resume airing on [[Creator/{{Toonzai}} TheCW4Kids]] in fall 2009, it never came to pass.
* WordOfGod: Original series co-creator Tom Tataranowicz has stated that he believes none of the Martian mice have last names and have avoided them altogether because surnames were considered a liability, and the Martian mice didn't need them because they could identify their relatives with no problems, though he has acknowledged that series creator Creator/RickUngar may have a different idea behind the Biker Mice's FirstNameBasis.
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