** Chris Hardwick plays Otis on the series. Most people may know him from the G4 series ''Series/WebSoup'' as well ''Series/AttackOfTheShow'' (and later on, ''Series/AtMidnight'').
** Oh and Freddy is voiced by Creator/CamClarke , a.k.a. [[VideoGame/MetalGearSolid LIQUID SNAKE!]]
** ''WesternAnimation/DarkwingDuck'' fans will hear that Pig is Tino Insana, aka Bushroot.
** Hilly and Officer O'Hanlon are played by Creator/JohnDiMaggio.
** FredTatasciore as the Farmer
** Creator/RobPaulsen as Peck. They even made a ShoutOut[=/=]ActorAllusion to it when Freddy was trying to come up with a new catchphrase and he says "Hey, what about [[WesternAnimation/PinkyAndTheBrain narf?"]] and Peck says "Nah."
** Creator/JenniferHale and Creator/TomKane as Freddy's Mom and Dad
** Music/GreyDelisle as Abby's cousin Betsy
** [[WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius Sheen]] [[WesternAnimation/PlanetSheen Estevez]] (Jeff Garcia) is Pip.
** [[WesternAnimation/HeyArnold Ernie Potts]] is Duke.
* TheOtherDarrin: Otis - Kevin James (movie) and Chris Hardwick (series).