!!1963 TV series
** Kazue Tagami voiced Astro in episodes 97-106 while Mari Shimizu was on maternity leave.
** Uran was first voiced by Yoko Mizugaki, then by Reiko Mutou, then by Kazuko Yoshikawa.
** Higeoyaji was first voiced by Masaaki Yajima, then by Ayao Wada.
** Tawashi was first voiced by Shingo Kanemoto, then by Kouichi Chiba.
!!1980 TV series
* HeyItsThatVoice: Mari Shimizu reprised her role as Astro. Hisashi Katsuta also reprised his role of Ochanomizu.
* Osamu Tezuka wrote the lyrics for the first ending theme [[http://www.youtube.com/watch?v=OAEFGdJNt_s "Mirai ni Mukatte - New Tetsuwan Atom."]]
!!2003 TV series
** The English dub has GregCipes as Atlas, Creator/CandiMilo as Astro, and LaraJillMiller as various episode-specific characters.
** Hisashi Katsuta, who voiced Ochanomizu in the previous two anime adaptations, voices him once again in this series.
* NamesToKnowInAnime: The main writer for this series was ChiakiKonaka. Seriously. In fact, he was invited right after (and presumably due to) having worked on ''Anime/DigimonTamers''.
** The movie has [[CharlieAndTheChocolateFactory Freddie Highmore]] as Astro, Creator/SamuelLJackson as Zog, Alan Tudyk as Mr. Squeegee, NicolasCage as Dr. Tenma, BillNighy as Dr. Elefun and Bill the Fridge, Creator/EugeneLevy as Orrin, Donald Sutherland as President Stone, [[WhoseLineIsItAnyway Ryan Stiles]] as Mr. Mustachio, and Nathan Lane as Hamegg.
** MegumiHayashibara voiced Cora in the Japanese dialogue version.