* AllStarCast: Music/JenniferLopez, Creator/JonVoight, Music/{{Ice Cube}}, Creator/EricStoltz, Creator/OwenWilson, Creator/JonathanHyde and Creator/KariWuhrer. Yeesh.
* FakeNationality: Paraguayan Paul Sarone is played by American actor Jon Voight.
* ThrowItIn: During the filming of one scene, the controls for the animatronic anaconda shorted out, causing it to completely lose control. Some of the footage is included in the movie.
* UncreditedRole: Mark Haskell Smith was responsible for much of the shooting screenplay, but went uncredited for his work.
* WhatCouldHaveBeen:
** Creator/GillianAnderson was considered for Terri and Denise.
** Creator/JenniferAniston was considered for Terri Flores.
** Creator/CameronDiaz was considered for Denise Kalberg.
** Creator/SeanConnery, Creator/TommyLeeJones, Creator/JohnMalkovich and Creator/JeanReno were considered for Paul Serone.
** Creator/WillSmith was considered for Danny Rich.
** Creator/MichaelJFox was considered for the role of Dr. Steven Cale. Rather ironic, considering that he was ultimately played by Creator/EricStoltz, an actor Fox famously replaced in [[Film/BackToTheFuture1 another film]] to the point of [[TheOtherMarty naming its own trope]].
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