* EnforcedMethodActing: While shooting the scene where [[spoiler: a dying Mozart dictates the Requiem to Salieri]], Tom Hulce deliberately skipped lines so as to make it seem [[spoiler: Salieri could not understand what he was being dictated]].
* HeyItsThatGuy: That's a surprisingly young [[Series/SexAndTheCity Cynthia Nixon]] as the maid who comes to work for the Mozarts ([[spoiler:secretly hired by Salieri to spy on Wolfie]]).
** Jeffrey Jones, better known to most as [[Film/FerrisBuellersDayOff Principal Rooney]] or [[Film/TheHuntForRedOctober Skip Tyler]], plays Emperor Joseph.
** [[Film/AnimalHouse Pinto]] is Mozart!
* TheOtherMarty: Meg Tilly was originally cast as Constanze Mozart, however, she tore a knee ligament the day before shooting started, thus being replaced with Elizabeth Berridge.
* RevivalByCommercialization: According to TheOtherWiki, the film ironically helped spark a revival of Salieri's music, which had previously languished in obscurity.
* WhatCouldHaveBeen:
** Creator/MarkHamill was considered for the role of Mozart (for the film) and he had already played the role on Broadway. He was rejected because the director wanted lesser-known actors.
** KennethBranagh, Tim Curry and Mel Gibson were among those rejected for the part of Mozart.
** Meg Tilly was originally supposed to play Mozart's wife but she injured her leg the day before filming and the part had to be recast. Director [[Creator/MilosForman Miloš Forman]] did later hire her again for a another period film set in the 18th century, ''Valmont'' (based on the novel ''Literature/DangerousLiaisons'').