* TheDanza: Michael Vaughn (played by Michael Vartan) and Rachel Gibson (Rachel Nichols).
* DirectedByCastMember: Jennifer Garner called the shots on "In Dreams...".
* FakeNationality: A lot of it.
** FakeBrit: David Anders is American. You'd never know it from his performance.
** FakeRussian:
*** None of the actresses playing the Derevko sisters are Russian: LenaOlin (Irina) is Swedish, Isabella Rossellini (Katya) is Italian, and Sonia Braga (Elena) is Brazilian.
*** Julian is one as well, as we find out in Season 3. Sark isn't his real name, and his father is a descendent of the Romanov family.
** Gina Torres, who plays half-Russian, half-Spanish Anna Espinosa, is neither Russian nor Spanish. She's half Cuban, half African-American.
* HeyItsThatGuy:
** Amy Acker will forever be known as [[Series/{{Angel}} Winifred Burkle]]. Or, depending on your flavor of [[JossWhedon Whedon]], [[Series/{{Dollhouse}} Dr. Saunders]].
** Anna Espinosa (GinaTorres) would later turn good and become [[Series/{{Firefly}} Zoe Washburne]].
** Weiss became [[Series/{{Heroes}} Matt Parkman]] and was in BASEketball! Also, Sark became [[Series/{{Heroes}} Adam Munroe]], [[Series/TwentyFour Josef Bazhaev]], and [[VampireDiaries Uncle John Gilbert]]!
** One of the biggest has been Bradley Cooper, who played Will Tippin and is now a bonafide "movie star" (''Wedding Crashers'', ''The Hangover'', and the remake of ''Film/TheATeam'').
** Jack Bristow was [[Film/{{Titanic}} sorry he couldn't build a better ship]] for KateWinslet, and was [[{{Film/Godspell}} Clown Superman in suspenders]].
** Vaughn gave [[NeverBeenKissed Drew Barrymore her first kiss]]
** Ariana Kane, head of Counterintelligence for the Alliance [[OutlawCouple was once a famous criminal]]
** Edward Poole, head of SD-9 once had a [[Film/JamesBond license to kill]] (yep, Roger Moore)
** Martin Shepard, an amnesiac assassin [[TheMummyTrilogy once fought Mummies with Brendan Fraser]]
** F.B.I. Assistant Director Kendall would end up [[Series/{{Lost}} on a wheelchair and stranded on an Island]]. (He was also the [[Series/TheWestWing Chairman of the Joint Chiefs]].)
** And Kelly Peyton [[Series/{{Angel}} once worked for a badass vampire with a soul and became the vessel]] for an EldritchAbomination.
** Arvin Sloane turned into a [[BrothersAndSisters winery owner]].
** [[Creator/QuentinTarantino McKenas Cole]] and [[Creator/DavidCronenberg Dr. Brezzel]] moonlight directing movies.
** [[Series/{{Castle}} Kate Beckett]] worked as a stewardess briefly.
* StarMakingRole: For Creator/JenniferGarner.
* WhatCouldHaveBeen: Roger Moore's role as Edward Poole was originally planned to be recurring, but Moore and the producers couldn't agree on his salary so the character was killed offscreen a couple episodes after his first appearance.