* DawsonCasting: Several of the cast members, including Jasmine Guy, Kadeem Hardison, and later Karen Malina White in the show's final season, were in their mid-20s when they were cast as Hillman students.
** Ironically, not so with Dawnn Lewis/Jaleesa, who was supposed to be older than the other students. Jaleesa was said to be 26 at the start of the series and Dawnn Lewis was in real-life.
* DirectedByCastMember: Jasmine Guy, Kadeem Harrison and Glynn Turman directed episodes from time to time.
* HeyItsThatGuy: Terrell Walker (season 6, played by Patrick Malone) Prior to ''Series/ADifferentWorld'', Malone had appeared in episodes of ''[[Series/TwentyOnejumpStreet 21 Jump Street]]'', ''Series/BeautyAndTheBeast'', and ''Series/ChinaBeach''. He also played Henry Lamb (the boy hit by the car) in the 1990 film ''[[Literature/TheBonfireoftheVanities The Bonfire of the Vanities]]'' and Otis (Danny Glover's troubled nephew) in 1991's ''Film/GrandCanyon''. After ''Series/ADifferentWorld'', Malone made guest appearances on over 25 different TV series, including ''Series/{{CSI}}'', ''Series/DesperateHousewives'', ''Series/{{Dexter}}'', ''Series/LasVegas'', and ''Series/NCISLosAngeles''.
* HeyItsThatVoice: Yes, this is what Creator/CreeSummer, whose voice is a part of ''everybody's'' childhood, looks like.
* RomanceOnTheSet: Kadeem Hardison dated Creator/CreeSummer for a while during the show's run.
* WrittenByCastMember: Jasmine Guy wrote a handful of episodes.