* The title character of ''ComicStrip/FunkyWinkerbean'' was something of a pessimist as an adult, but still mostly a nice guy. After TimeSkip #2, he became a grumpy, avaricious JerkAss.
* [[Comicbook/{{Ant-Man}} Hank Pym]] in the Franchise/MarvelUniverse, though this fluctuates DependingOnTheWriter.
* Although he was already kind of a jerk, Comicbook/IronMan during the Comicbook/CivilWar/SecretInvasion period was borderline approaching villain status. Thankfully, [[Film/IronMan the movie]] helped him to get the better of it.
* ''Franchise/{{Batman}}'' has an on-and-off again history of this. ''Comicbook/AllStarBatmanAndRobinTheBoyWonder'' probably takes the cake. Also to a ''[[UpToEleven huge]]'' extent in ''ComicBook/JLAActOfGod'', infamously.
* Nearly every incarnation of [[Comicbook/IncredibleHulk The Hulk]] goes through periods where he goes from [[TheWoobie Woobie]] to JerkassWoobie to just plain {{Jerkass}}.
** Then again, it's The Hulk. His superpower is taking a level in both badass and jerkass.
* Most of the NewMutants in recent years, but especially [[Characters/NewMutants Cannonball]].
** A ''New X-Men'' example with Hellion. While already a tremendous ass to begin with, he somehow ''still'' managed to take another level after his hands got blow'ed up by Bastion.
* [[{{Sub-Mariner}} Namor]] with his oxygen-processing problem.
* PowerGirl with her diet soda processing problem.
* In his earlier appearances, Curt Connors of ''Comicbook/{{Spider-Man}}'' was a reasonably sympathetic character when he wasn't [[SuperpoweredEvilSide the Lizard]], and even as the Lizard retained some protective instincts towards his family. He was {{retcon}}ned into being EvilAllAlong, and as of ''The Gauntlet'' he [[spoiler: completely lost control of the Lizard persona and ''killed and ate his own son'']]. After that, his more sympathetic characterization likely won't be coming back any time soon.
** The EvilAllAlong ret-con was pretty much ret-conned itself after the story that introduced the idea, as no other writer has used it since then.
* Natalie "Envy" Adams from [[Comicbook/ScottPilgrim Scott Pilgrim Volume 3]] took a several year course in jerk-assery and passed with an A+++.[[spoiler: In college, "Nat" used to be a nerd who had a lot of anime stuff in her dorm, didn't see the point of partying hard, and dated Scott for a long while. Her, Scott, Stephen Stills, and two insignificant others started a band called "Kid Chameleon" that ended up becoming pretty popular, eventually cornered by record labels. Having undergone some character development, she wanted to sign the band up to a label against Scott's (the band founder's) wishes, who just wanted to make a band to have fun and meet chicks. Being in a popular band apparently made her much less shy and she became more confident in herself. But in the bad way. She ended up becoming a huge bitch that virtually no other character liked that broke Scott's heart and started a band with Todd Ingram, her boyfriend and Ramona's third evil ex-boyfriend, and a drummer named Lynnette Guycott that Todd ended up cheating on Envy with.]] And for some reason or another, she started hating her real name, insisted everyone called her Envy, and started smoking, something Scott detests rather greatly (not that any of that stuff is super-relevant, just sayin').
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