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* Rasoul and 2/3 (can't remember the exact amount), Royal Guards from ''Disney/{{Aladdin}}''.
* Lafayette and Napoleon from ''Disney/TheAristocats''
* Lumiere and Cogsworth from ''Disney/BeautyAndTheBeast''.
* The moose Rutt and Tuke in ''Disney/BrotherBear''.
* The rats Nick and Fetcher from ''WesternAnimation/ChickenRun''.
* Mub and Grub in ''WesternAnimation/{{Epic}}'' .
* There were two loggers operating the leveler in ''WesternAnimation/FernGully'' that fit the trope.
* [[IsntItIronic Dinky the sparrow and Boomer the woodpecker from]] ''Disney/TheFoxAndTheHound''. Not the kind of animals you'd expect from a movie with that title.
* Crash and Eddie in the ''WesternAnimation/IceAge'' movies.
* Timon and Pumbaa from ''Disney/TheLionKing''. They later got [[RecycledTheSeries their own series]], and their own movie.
* Needleman and Smitty from ''WesternAnimation/MonstersInc''.
* Jasper and Horace in ''Disney/OneHundredAndOneDalmatians''. This goes for the live action film too.
* Honest John the fox and Gideon the cat in ''Disney/{{Pinocchio}}''.
* The two jet fighters in ''WesternAnimation/{{Planes}}''.
* Ben and Lon from ''Disney/{{Pocahontas}}''.
* Nico and Pedro from ''WesternAnimation/{{Rio}}''.
* According to WordOfGod, Miguel and Tulio of ''WesternAnimation/TheRoadToElDorado'' are Those Two Guys recast as protagonists because the writers had seen so many memorable sidekicks upstage the boring heroes.
* Br'er Fox and Br'er Bear in ''Disney/SongOfTheSouth''.
* Snake and Robot from ''WesternAnimation/ToyStory''
* Bobble and Clank in [[Franchise/DisneyFairies Tinker Bell]].
* DonBluth does this quite a bit in his Nineties films.
* Puss and Donkey in ''WesternAnimation/ShrekTheThird''.
* Goblins Stuff and Thang play this role in ''WesternAnimation/StrangeMagic'' though its [[GenderReveal revealed]] at the end that one of them is [[DudeLooksLikeALady actually a female]].
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