* ''WesternAnimation/CorpseBride'' does this twice. First, the opening song, "According to Plan", is all about how "every tiny microscopic little thing" must be just perfect for the wedding. You couldn't be asking for it ''more''. Then, later, when Barkis is making his [[spoiler: wedding toast]], he says, "No force on Earth can tear us apart!" [[spoiler: Cue the invasion of the walking dead.]]
* ''WesternAnimation/ToyStory'':
** "'It's safer in the cockpit than the cargo area'... what an idiot."
** "What could ''possibly'' be worse than you?" [[spoiler:Subverted in WesternAnimation/ToyStory2, where the toys and the new puppy have become friends.]]
** In ''WesternAnimation/ToyStory3''.
--> [[spoiler:Rex: I think that's daylight! *Cue incinerator*]]
* ''TheIncredibles'': "We're superheroes. What could happen?" Actually happens twice, with the same result.
* ''WesternAnimation/FindingNemo'': "No, I've never met a shark, and I don't plan to."..."Well, if I ever meet a sea turtle, I'll ask him... right after I'm done talking to the shark."
* ''Disney/ThePrincessAndTheFrog'': "I've climbed a mountain, I've crossed a river, and I'm almost there!" To be fair, she had already made it past a number of obstacles -- being a young, black, poor, woman... It was just that the magic took it to a whole new level of obstacles, and she couldn't have anticipated that!
* In the Hungarian cult film ''CatCity'', mice are on the good side, and cats are criminals. At the beginning, a bank clerk assures a worrying client that to this bank, cats could only break into with a tank. Guess what happens next. And his very next line...
-->'''Clerk:''' No! Over my dead body!
* Played with in the first ''TheBraveLittleToaster'' movie:
-->'''Radio:''' Things could be worse, you know!\\
'''Lampy:''' How?\\
'''Radio:''' How what?\\
'''Lampy:''' How could they be worse?\\
'''Radio:''' ''(after a beat)'' They couldn't. I lied.
* In ''PrincessMononoke'', Lady Eboshi recommends caution with wounded opponents:
-->'''Eboshi:''' Cut off a wolf's head, and it still has the power to bite.
** [[spoiler: She's got the courtesy [[LampshadeHanging to deliver]] her own IronicEcho, though.]]
* ''Film/WhoFramedRogerRabbit''.
** While Roger is standing guard inside Maroon Studios he says "No one gets the drop on Roger Rabbit!" Seconds later he's [[TapOnTheHead conked on the head and knocked out]] by a frying pan.
** Lampshaded later when Jessica says the only reason she knocked him out and stuffed him in the trunk of a car was because she didn't want him getting hurt. Lampshadeded ''again'' when Eddie responds with obvious irony, "Yeah, that makes perfect sense."
*** Well, it would make perfect sense to a ''toon''.
* The Earthworm in ''Film/JamesAndTheGiantPeach'', as he ponders what kind of bait would be good for seagulls.... ahem.
* ''WesternAnimation/KungFuPanda'': "Escape from Chor-Gom Prison is ''IMPOSSIBLE!''" [[spoiler: Tai Lung likes a challenge]]
* ''WesternAnimation/ABugsLife'' has Hopper tempt fate upon seeing a bird standing right above him. To be fair, fate was CryingWolf earlier on, seeing as how the last bird Hopper saw before then turned out to be a fake one designed by Flik, and said bird showed up while Hopper was trying to strangle Flik. Still, it is interesting that his last words (aside from the screaming) were being said to Flik upon them seeing said bird...
-->'''Hopper:''' Well, what's this? [[YourLittleDismissiveDiminutive Another one of your little bird tricks?]]
* ''YellowSubmarine''. Ringo says "Nothing ever happens to me." Cue the title vehicle's appearance.
* ''Disney/TheAristocats'': "You're going to Timbuktu, if it's the last thing I do!" [[spoiler: (cue a bunch of alley cats led by Thomas O'Malley subduing Edgar, then shoving him into the very crate he was going to use to send Duchess and her kittens to Timbuktu, and as a result, it's now Edgar that's the one going to Timbuktu)]]
* Towards the end of {{Disney|AnimatedCanon}}'s ''Disney/TheHunchbackOfNotreDame'', [[spoiler:while Esmeralda is holding Quasimodo up over the edge of a building, while Frollo close by is standing, above a pool of molten copper, on a stone gargoyle, while carrying a sword, and says "and [[{{God}} he]] shall smite the wicked, and plunge them into the fiery pit!" [[KarmicDeath Remember what happened after that]]?]]
* Disney/BrotherBear. [[NoAnimalsWereHarmed "No fish were harmed during the making of this movie."]] [[spoiler: Cue some random fish [[CarnivoreConfusion swimming away screaming while being chased by a bear,]] followed by Koda turning toward the camera and blushing before covering the lens, ending the film.]]
* The premise of the song "I Just Can't Wait to be King" from the film ''Disney/TheLionKing''. Unfortunately, becoming king has a fairly drastic requirement...
* In ''WesternAnimation/{{Shrek the Third}}'', Shrek is called to King Harold's side. Already annoyed by the kingly duties placed on him during Harold's sickness, he yells, "Someone better be dying!" That someone turns out to be Harold himself.
* Disney/{{Pinocchio}}. "Hear that beetle talk; you'd think something was gonna happen to us." [[spoiler: Cue Lampwick turning into a donkey.]]
* The song "There Are No Cats in America" from ''WesternAnimation/AnAmericanTail''. However, it turns out that there ''are'' cats in America.
* In the 2012 version of ''WesternAnimation/TheLorax'' The Once-ler delivers the line "I attend to keep biggering and BIGGERING, and turning more truffula trees into thneeds! AND NOTHING IS GOING TO STOP ME!" right before the final truffula tree falls.
* {{ParaNorman}}:
--> '''Perry Babcock''': Where are the police when they are needed!?\\
''Cue Sheriff Hopkins crashing her cycle into the Babcock's car, slides across the car and rams into Perry''.
** In another example, Norman arrives at the graveyard near Mr. Prederghast's home with the book, and reassures himself that all he's got to do is read it, stop the curse, and then go home and continue life as usual. [[WhatCouldPossiblyGoWrong Sounds easy enough.]] [[spoiler: Except he's reading it in the wrong spot. The curse goes off anyway, causing all hell to break loose.]]
* ''{{Hoodwinked}}'': Red is riding a cable car with Boingo.
-->'''Boingo:''' Hey, you deliver up this far?
-->'''Red Puckett:''' Well, not usually. But I was thinking about what you told me earlier - about the Muffin Man? I need to protect Granny's recipes from that bandit's evil plan. They're gonna shut down everyone in the forest if we're not careful.
-->''(Cue tram car doors flying open and Red struggling to keep her balance)''
-->'''Boingo:''' No! ''(One second later, Red falls)''
* In ''[[{{Disney/Aladdin}} Aladdin and the King of Thieves]]'' during the opening song, Genie (imitating WalterCronkite) asks "What can possibly go wrong?" before the forty thieves sing their verse proclaiming they will rob the party.