* Both versions of the story of Ice and Snow [[spoiler: / Ice and Dark]]

* The ending of episode 14, when Daisuke, alone in the darkness of his bedroom, [[spoiler:silently pulls a veil over his painting of Risa, signifying that he's finally realized she doesn't return his feelings.]] Also counts as MoodWhiplash in contrast with the rest of the episode, which dealt largely with the antics of the school's new ForeignExchangeStudent and super GenkiGirl Mio Hio.
** This troper cries every time he watches the end of this particular episode... I literally have to watch the next episode just for a change in mood.
* Speaking of Mio, [[StepfordSmiler her whole predicament]]. [[spoiler: She's a living voodoo doll who desires to be human, but in order to achieve this, she has to sacrifice Daisuke, whom she comes to genuinely care for]] She eventually [[spoiler: negates the effects of the charms she gave Riku and Daisuke, [[HeroicSacrifice sacrificing]] not just her chance for a human body but her doll body as well.]] And although for a while she appears as an annoying cockblocker for Daisuke and [[spoiler: Riku]], she actually [[IWantMyBelovedToBeHappy ends up]] [[ShipperOnDeck being greatly supportive of them]] in the end, telling [[spoiler: Riku]] that she and Daisuke are a great couple together, in the midst of [[spoiler: [[DisappearsIntoLight vanishing,]] which is a Tearjerker in universe, as both Riku and Risa are crying as it happens.]]
* Manga volume 13 - Stage 3, vol 21: Daisuke's reaction to Satoshi telling him that [[spoiler: his family are cursed to die young]] is to almost break down into tears and say they have to '''do something''' while ''clinging to Satoshi's arm''. Satoshi is absolutely shocked - has a flashback montage of many happy moments spent together with Daisuke - and then does the closest thing to a fond smile he can do. The HoYay shoots back UpToEleven for the whole chapter, but in a very, very serious and heartbreaking way for once.
* Stage 4, vol 14 is also quite the TearJerker, and in quite the same fashion as above; if you didn't think Satoshi was a {{Woobie}} before, you sure do think so ''now''.