!!!From the comics

* ''Explorers on the Moon'': [[spoiler:Wolff, overcome with guilt at betraying the others, leaving the rocket and marooning himself in space in the hope that it will give the others more oxygen; even Captain Haddock, who moments ago thought Wolff had actually tried to commit sabotage, is moved to tears by this.]]
* ''Tintin in Tibet'': [[spoiler:The Yeti's grief when Chang leaves.]]
--> '''Chang''': [[spoiler: People treat him like an animal, but I belive he has the soul of a man]]
** There's also the Captain trying to [[HeroicSacrifice sacrifice himself]] to save Tintin, along with Tintin's reaction to his plan.
--> '''Captain Haddock''': "You can at least save yourself. You must cut the rope, it's the only answer!"
--> '''Tintin:''' "Never! Either we're both saved, or we die together!"
** Another one, when they arrive at the crashed airplane. The scene is already sad. And then Tintin finds a teddy bear... Thanks to FridgeHorror, we may easily guess what it means.
* Snowy's reaction to Tintin being [[spoiler: supposedly]] killed by firing squad in "Cigars of the Pharaoh". He's so upset that he decides to lie down and die on Tintin's grave. [[spoiler: Thankfully, he learns that Tintin's still alive]].

!!!From the animated series

* In the scene in "Tintin in Tibet" where Haddock tries to sacrifice himself, he mutters bitterly to himself that he's "just getting rid of dead weight" while trying to cut the rope, which makes the scene all the more painful.
** In the same episode, when Tintin finds the teddy bear (see above), Haddock says a line that's far more heartbreaking when it's heard than when it's read.
--> '''Captain Haddock:''' "Couldn't you find something else?"
** Haddock reading the article about the plane crash, and the realization that it's the plane Chang was on.
--> '''Haddock''': The plane was carrying a team of scientist, as well as...a...young, chinese boy...
--> '''Tintin''': *with tears in his eyes* ''Chang''! My poor friend Chang...