* The episode where Scully's cancer is diagnosed is a direct and shameless heartstring-twister from start to finish. It works.
* The scene in "Redux II" where Scully tries to get Mulder to pin the death of a man he killed on her -- because she doesn't want him to go to prison, and she's going to die soon anyway. The look on Mulder's face is just heartbreaking.
* "The Unnatural", baseball, fun-loving aliens, the gospel and song and finally ''It's just blood''. The death of the alien who made such a good human is very heart-wrenching.
* The last twenty minutes of "Emily".
* The ending of the episode "The Post-Modern Prometheus". The whole scene works on two levels and depends on how one interprets the writing. It feels very heart-warming, but considering that it's what Mulder told the writers (the boy who wrote the comic or even the writers of the show -- very appropriate for {{Postmodernism}}) to appeal for a better ending, it might very well be just something what he wishes to happen for the monster and for himself. Which makes it more of a truly tear-jerking moment.
* The episode "Trustno1", especially the e-mails between Mulder and Scully -- poor Mulder just wants to come home.
* The tear-jerking scenes from the "Within"/"Without" episodes, notably when Scully goes to Mulder's apartment, finds his shirt and falls asleep on his bed clutching it tightly.
* The episode "Roland" was heartrending, especially the end where Roland leaves his home and gives Tracy his jar with the stars. Horrible that they like each other so much and must be separated.
* The end of "Closure", where Mulder finally comes to terms with Samantha's disappearance. The fact that [[http://www.youtube.com/watch?v=ZFzogfFw-2Q this Moby song]] is playing in the background probably increases the sadness tenfold.
* Whenever Scully breaks up and is NotSoStoic, chances are it's going to be a Tear Jerker. Just look at the ending of "Irresistible". She is always such a strong and capable woman, and very hard on herself. When she finally let Mulder comfort her...
* The ending of "Release", with Doggett and his wife spreading [[spoiler: their son's]] ashes into the ocean.
* All of "Kaddish", especially the story behind the wedding ring. Poor couple, they could have been so happy together.
* When Doggett's amnesia in "John Doe" gets broken by the memory of his murdered son. It's the only time we ever see him cry.
* The ending of "Hungry".
-->'''[[TragicVillain Rob Roberts]]:''' I can't be something that I'm not.
* Scully's distress after shooting the MonsterOfTheWeek in "Badlaa", which had taken the form of [[spoiler:a child]].
* The end of "Jump The Shark" for [[spoiler:fans of The Lone Gunmen with their deaths]].
----