* Tenebraum's [[spoiler:death scene]]. Specially because of the MoodWhiplash: [[spoiler:Tenebraum is apparently just grazed by an arrow, soon she begins collapsing, then Lachrymarum and Suspiriorum [[LikeYouWouldReallyDoIt don't initially believe she's about to die]], and ''then'' they realize it's for real...]]
--> [[spoiler:'''Lachrymarum:''' ... We should all be together.]]
* The reader can't help but feel sad about how much Peace's death has affected the Sleuth Brigade.
* Kurosawa goes to Snark's cafe to confess to her... [[spoiler: [[BuryYourGays he doesn't come back out alive]].]]
** And later, [[spoiler:he tries to warn Mamiya against the idea of killing Taizou, as per her newest "job", since he senses that she's a good person underneath the snark and roughness.]] [[spoiler:She doesn't listen, [[OffWithHisHead and holy shit does she pay for it]].]]
* [[spoiler:Tenebraum and Professor break up.]] That [[spoiler:Professor]] is so optimistic is just...
** The fact that [[spoiler:they broke up because she unintentionally used up all of the power that was slowing down her decaying to heal him from being crippled [[ItsNotYouItsMe and is too ashamed to let him see her as she is]]]] just makes it all the sadder.
** Later on, [[spoiler:Elena and Beluna visit Tenebraum. She's mostly healed back to the state she was in when the Sleuths first found her, but [[LaserGuidedAmnesia she can barely recognize her sisters]]. After the time skip, it's revealed that Professor visits her once a week without fail, because she loses the memory of meeting him soon after he leaves]]. With her mental decay and loss of bowel control, she's very much like a mid- to late-stage Alzheimer's victim.
* Elena goes to visit her mother and teacher in Russia, and returns to find [[spoiler:Taizou being brutally tortured by Yakuza, including having [[FinGore his fingers]] and [[EarAche one of his ears]] cut off, [[TheToothHurts some teeth pulled out]], '''and''' [[EyeScream one of his eyes put out]]. (In fact, [[ChekhovsSkill had she not accidentally moved his heart a little to the left]] during a PsychicSurgery, he'd have been killed.]]) She walks towards [[spoiler: the almost dead Taizo]] as if in a daze, even ignoring one of the Yakuza when he hits her on the head [[EyeScream and cracks her glass eye]]; she gently apologizes to [[spoiler:Taizou]] for [[spoiler:not having been there to protect him]], and then [[TranquilFury calmly]] enlists the others' help in [[LudicrousGibs repainting the room]]...
* When [[spoiler:Demona comes to collect Snark's soul as an effect of her DealWithTheDevil, Snark's last wish is... to properly say goodbye to her little sister Alice. She cannot tell Alice she's about to die and go to Hell, but still asks her to be happy in her life.]]
* [[spoiler:Mamiya's partner and little sister is [[HalfTheManHeUsedToBe chopped off in parts]] by Snark, when she goes LeeroyJenkins on her during a squabble to see who will kill Taizou. [[ApologeticAttacker Snark is very unhappy about the idea]], [[WouldHurtAChild but does]] [[WouldHitAGirl it anyway]].]] Then [[spoiler:she's stitched back to health by Beluna, on the condition [[GetOut that she leaves and never returns]]. She's last seen on a plane, swearing she'll sooner or later get her revenge...]]

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