* In the end of the fifth stage of the original Splatterhouse from 1988, Rick's beloved [[DamselInDistress Jennifer]] (roughly) uttered the words "Oh, my darling.", and then mutates into [[TragicMonster a hideous clawed beast]]. It [[LaughingMad lets out demented cackles]] before and while fighting Rick. During the fight, Jennifer reverts to her normal self and begs Rick to save her before the monster takes over again. After the battle, Jennifer tragically dies in Rick's arms, but not before thanking Rick, and before she dies in Rick’s arms, she says, “Goodbye...” as [[https://m.youtube.com/watch?v=1hOSgb1OrjM&list=PL7E2K_QNya5XgDhrObw6oAIJvaFBe7WLT&index=21&t=0s this]] begins playing. You do save her in the sequel, but for the time, it was a depressing twist.
* All three of the bad endings of ''Splatterhouse 3''. While Rick saves the world from the chaos the Terror Mask intended to unleash, he's still devastated by his failure to save his wife and/or son, and the Terror Mask twists the knife by reminding Rick that it will return [[AsLongAsThereIsEvil as long as he is suffering]].
** Failing to save Jennifer in time while succeeding in saving David ends with Rick a single father having to explain to his son that his mother is dead.
** If you succeed in saving Jennifer, but not David, Jennifer will ask Rick where their son is and react to Rick's answer with "[[LittleNo No....!]]".
** Should you fail to save both of them, Rick is implied to be [[DespairEventHorizon driven insane by the loss of his family]].
--->'''Rick:''' "Alone. All alone..."
* Dr. West in the remake as a whole. His heart was utterly broken by his wife's suffering, so he made a deal with the Corrupted to try and save her. For his troubles, she only ended up becoming a monster and was nearly burnt alive in a sacrificial wicker man before Rick went back in time and killed her after making an effort to save her, mistaking her for Jennifer.
* The ending in the 2010 remake. After taking down the Overlord, [[DownerEnding the game ends with]] [[DemonicPossession Jennifer getting possessed by the Corrupted]] just before the gateway was closed off. [[TheBadGuyWins Dr. West succeeded]] with his plans of bringing his wife back from the dead, and Rick is left with a former shell of his beloved girlfriend.
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