* After seeing his magic act, a WheelchairWoobie cries out to Oz "Make me walk!". Being simple country folk, even her parents beg him to use his magic and offer him money. Oz is shocked and dismayed, and clearly feels bad that he can't do anything to help, but tells her that there is a 'distemper'. He is then booed off stage. Frank tells him later that he should have told her the truth.
* China Girl's introduction, in which her village is destroyed by Evanora and her legs are broken off. Her bitter weeping when she is revealed with her broken legs and tells what happened to her family is especially distressing; even Oz can only look at her silently before he finally [[ChekhovsGun thinks of a solution]]. What makes it even more moving is that it's a CallBack to the prologue in Kansas, where we see Oscar failing to help a girl in a wheelchair who asked him to help her walk again. That girl was played by Joey King, the same actress who voiced the China Girl - and Oscar couldn't afford to let her down again.
** Turns into a CrowningMomentOfHeartwarming when Oscar then gives her a hug.
* Theodora's moment of realization - too late - right after biting that apple may qualify.
** Oh, it ''and'' what follows qualifies...[[spoiler: First comes the pain, then the madness, and then there's nothing left but ''the hate'']]. It's tragic, powerful stuff.
** Theodora reassuring her sister that all she wants is peace. This becomes HEARTBREAKING later on when [[spoiler: she has become fully wicked and talks of drenching the yellow brick road in the blood of Oz' citizens, or laughing at what she thinks are those people being mauled by her flying baboons.]]
** Oscar and Glinda are far from unaffected by [[spoiler:Theodora's transformation.]] Oscar seems genuinely horrified once he gets over the shock, while Glinda is just sad because she'd hoped [[spoiler:Theodora would see through her sisters lies.]]
* When [[spoiler:Oscar fakes his death,]] and it makes Finley and China Girl weep.
** Even Glinda seems devastated.
* After Theodora's [[spoiler:RedemptionRejection]] at the end, Oz's face at [[spoiler:his realization [[MyGreatestFailure that his]] [[TheCasanova careless and mindless flirting]] [[MyGodWhatHaveIDone is what led an innocent and pure hearted girl to turn evil]]]] is shattering.