When the game goes into {{Wham|Episode}} overdrive, expect ''a lot'' of these moments:
* Liu Kang. [[spoiler: He goes through a TraumaCongaLine in this game. He witnesses his best friend get murdered, watches as his beloved dies in his arms, and ends up burnt to a crisp by Raiden, believing that the very god he revered had failed him and his friends.]]
** There's added [[FridgeLogic Fridge Sadness]] in Liu Kang's non-canon arcade ending, where he ends up [[spoiler:surviving to kill Kahn, and, from the sound of things, at the very least a few other fighters in addition to Sonya and Johnny Cage survive. It gets sad when Liu Kang ends up seeing Raiden as a burden throughout the whole ordeal, and ends up killing him in order to usurp his position and protector of Earthrealm.]] The implication is basically that no matter the outcome, Raiden's meddling has permanently ruined [[spoiler:one of his greatest friendships,]] and there's absolutely nothing that can change that short of simply letting Armageddon happen and losing everyone all over again.
*** And even worse, there's a continuation on that non-canon arcade end! Which is... [[spoiler:''Shang Tsung's''. It turns out taking over Raiden's place made Liu Kang DrunkWithPower and became a tyrant that Bo Rai Cho had to train his former archnemesis to stop him. It's basically either die from Raiden's meddling, die from Armageddon or live on to see himself become evil. It's official, Liu Kang's fate sucks either ways.]]
** And speaking of [[spoiler:Kitana, her DiedInYourArmsTonight speech to Liu Kang was pretty heartwrenching, as she laments that she wished that she was able to meet her lover under different circumstances. Doubly so, when you realize that she had it just as bad, if not ''[[TheWoobie worse]]'', in the original timeline ([[HeartbrokenBadass with Liu Kang dying and all]]). The girl's got it ''rough''.]]
** You think Kitana had it bad when she died in Liu Kang's arms? Let's try [[spoiler:meeting her mother again for the first time in thouasnds of years, aka ''the scene that put her in that position''. TearJerker and NightmareFuel together only begin to describe it. Seeing your mother, who you just found out had sacrificed herself to save your love interest's homeworld from sharing the fate of your own world at the hands of the tyrant who raised you as "his" daughter, come in and mercilessly beat on you and your friends, kill several of them with her bare hands, point blank disown you to your face, and ultimately kill you in the end, all with a look of sheer [[BrainwashedAndCrazy insane evil joy]] on her face, has to be, both literally and figuratively, one of the most soul-ripping experiences a fictional character has ever endured at the hands of a loving parent.]]
* The ending of the game. [[spoiler: All of the heroes end up dying save for Johnny Cage, Sonya and Raiden. To elaborate, Kung Lao gets a NeckSnap courtesy of Shao Kahn, Nightwolf does a HeroicSacrifice, Sindel performs a KillEmAll on the majority of the heroes, and Raiden accidentally fries Liu Kang to a crisp, with the latter's faith in him completely shattered as he dies.]]
** And, to top it all off: [[spoiler:Earth is now ripe for the picking for the Netherealm to take over.]]
* The very ''beginning'' of the game is a huge TearJerker as well, since all of your favorite characters are dead and the BigBad [[TheBadGuyWins stands triumphant.]] The music that plays as the camera pans across the lifeless bodies of the combatants does not help ease the tears.
* One that applies via a FreezeFrameBonus: [[spoiler:Kabal's life. If you look closely, he has a ''ring'' on his finger. He's most likely engaged/married, maybe with some children of his own. In the span of no more than a few hours, he's roasted alive, horribly disfigured, reanimated by Kano, and then killed by Sindel. And who's to say that his family wasn't caught up in the crossfire of Shao Kahn's invasion? The man genuinely wanted to turn his life around and renounced the life of a Black Dragon Clansmen to start anew, only to have this horrible fate befall him.]]
* Quan Chi showing Scorpion [[spoiler:the Shirai Ryu's destruction]] at the end of Chapter 3, especially considering that Scorpion [[spoiler:killed the elder Sub-Zero after, thus breaking the deal Scorpion had with Raiden ''that would have brought back his family and clan'']]. Oh, and canonically (this is, this particular bit is unaffected from the reboot) [[spoiler:[[MisBlamed it's not Bi-Han, but Quan Chi himself the one who really did this]]]].
* Smoke's [[spoiler:distraught over Kuai Liang!Sub-Zero]] at the end of Chapter 8. Johnny Cage's quip to Raiden sums it up as Smoke hangs his head in disbelief sums it up:
-->'''Cage:''' Sure. Let's go ruin someone else's life.
** With this in mind, his reaction to meeting [[spoiler:Cyber Sub-Zero]] at the end of Kabal's chapter.
-->'''Smoke:''' ...what they did to him....it is hideous.
* The game's BittersweetEnding. Watch [[spoiler:Sonya]] desperately struggle to hold back tears.