* Penny's death. This event caused the site to go through days of mourning for her and there was a swell of Penny-related artwork and depictions of scenes of the mourning pups when her body was brought back to camp.
* The deaths in ''Captured Kids of War'' nearly all of them caused heartache.
** Scamp, Geno and The Great Prince's deaths most of all.
* Sabor's death for Shere Khan. He can barely function afterwards.
* [[spoiler: Rebecca and Lucky's deaths]]. This is widely considered to be one of the most emotional and touching threads the site has ever seen.
* [[spoiler: Mauko's death.]] Nuka and Dotty were both devestated by the loss and no one on the site could have predicted how brutally the cub would die or how soon after his birth.
* Lady's death caused a chain reaction that all but destroyed her already crumbling family.
* Biff's death greatly effected Thomas seeing as he was Thomas's first dog