* [[TheAce Ace]]'s HeroicBSOD. After Mittens' transformation from BumblingSidekick to HypercompetentSidekick, [[http://www.commanderkitty.com/2011/02/20/occupied/ Ace begins doubting himself as a leader and falls into depression]], and later [[http://www.commanderkitty.com/2011/07/12/well-theres-yer-problem/ seems to have given up completely]]. He gets better, but his despair over having been apparently replaced by a younger, smarter spacer is surprisingly tragic.
* And when Ace ''does'' get better, [[http://www.commanderkitty.com/2011/09/11/you-know-youre-being-ignored-when/ poor Mittens ends up taking the brunt of him]] and becomes his old spineless self. While Ace treating him like dirt is at least [[MistakenForCheating a little justified]], you feel pity for him being stuck as the team's NoRespectGuy once again...
* After getting her real arm back, surviving Zenith's assault, and seemingly falling for CK, Nin Wah is [[RoboticReveal revealed to be an android clone]] [[http://www.commanderkitty.com/2011/12/11/did-you-try-rebooting/ and shuts down like all the other robots when Fortiscue deactivates the Zenith Project]]. Sure, we have the real Nin Wah back right after that, but her clone had become a character herself by this point, and the way she shuts down doesn't look particularly pleasant...
* And later, Android Nin Wah [[http://www.commanderkitty.com/2012/04/07/all-in-her-head/ gets laughed at by the original]] for remembering her history wrong, when just earlier it was revealed that [[http://www.commanderkitty.com/2012/01/01/seemed-like-a-good-idea-at-the-time/ clones actually have the memories altered]] by {{nanomachines}}. [[http://www.commanderkitty.com/2012/05/27/reporting-in/ The last we see of her for a while is her head just sitting on the shelf, seemingly resigned to her fate]].
* [[http://www.commanderkitty.com/2012/11/25/up-your-nose/ Zenith's current state]]. Whether [[http://www.commanderkitty.com/2010/07/04/nothing-like-a-good-rant/ ranting about conquering the galaxy]] or [[http://www.commanderkitty.com/2012/03/18/cks-epiphaly/ just happy]] [[http://www.commanderkitty.com/2012/08/15/nin-wahs-agenda/ to help]], she was always an expressive, entertaining character. Seeing her reduced to just a braindead calculator staring blankly with her ears and tail set aside in a box like any other spare part is a little heartbreaking, especially since she'd made Nin Wah [[http://www.commanderkitty.com/2012/08/15/nin-wahs-agenda/ a sweet new cyborg arm and outfit]] right before [[spoiler: [[http://www.commanderkitty.com/2012/09/09/she-dun-goofed/ Nin Wah herself inadvertently gave her a catastrophic system crash]]]].