* ''WesternAnimation/GuardiansOfLuna'' to ''WesternAnimation/{{Gargoyles}}''
* ''WesternAnimation/MickeyMouse'' to ''WesternAnimation/OswaldTheLuckyRabbit'': After losing Oswald to his distributor, Walt Disney created a new series of cartoons around a new character, Mickey, who was pretty much Oswald where the primary difference being that Walt Disney owned full legal rights to Mickey.
* The ''WesternAnimation/DonaldDuck'' cartoon ''WesternAnimation/TheNewSpirit'' (1942) was followed by the similar WarTimeCartoon ''WesternAnimation/TheSpiritOf43'' (1943), which even recycles the entire second half of this cartoon.
* ''WesternAnimation/HomeMovies'' to ''WesternAnimation/DrKatz'', with both shows employing the so-called "Squigglevision" animation (though ''HomeMovies'' dropped it in its later seasons).
* ''WesternAnimation/BobsBurgers'' to ''WesternAnimation/HomeMovies'', as both cartoons have a similar sense of humour and the voice of H. Jon Benjamin.
* ''WesternAnimation/SanjayAndCraig'' to ''WesternAnimation/BobsBurgers'', if not to ''WesternAnimation/AdventureTime'', because the former two share the same character designer while Adventure Time has Thurop Van Orman (who made ''Flapjack'') also working on it.
* ''WesternAnimation/{{Futurama}}'' to ''WesternAnimation/TheSimpsons''. Matt Groening, simple as that.
* ''WesternAnimation/AmericanDad'' to ''WesternAnimation/FamilyGuy'' before the latter was renewed. Even so though, and while it started out as the political version of the show, many people believe that ''American Dad'' is still the spiritual successor to the first three seasons of ''Family Guy''.
* ''WesternAnimation/CampLazlo'' and ''WesternAnimation/SpongebobSquarepants'' to ''WesternAnimation/RockosModernLife'' as all had similar teams working on them.
* ''WesternAnimation/TheJetsons'' to ''WesternAnimation/TheFlintstones''. There's also the much more obscure series ''The Roman Holidays''.
* ''WesternAnimation/TheAdventuresOfJimmyNeutronBoyGenius'' can be considered this to ''WesternAnimation/DextersLaboratory'' with the Kid Genius theme.
* ''WesternAnimation/MyLifeAsATeenageRobot'' to ''WesternAnimation/WhateverHappenedToRobotJones''. Other than the obvious robot theme, the show's creators both worked on each other's shoes.
* ''WesternAnimation/{{Animaniacs}}'' was more or less a continuation of ''WesternAnimation/TinyToonAdventures'' with a new cast of AnimatedActors.
** ''WesternAnimation/TinyToonAdventures'' to both ''WesternAnimation/LooneyTunes'' and ''WesternAnimation/APupNamedScoobyDoo'' (which was the last project most of the WBA staff worked on together at Hanna-Barbera).
** Within ''WesternAnimation/LooneyTunes'' itself, the short ''WesternAnimation/RabbitRampage'' could be considered the Spiritual Successor of ''WesternAnimation/DuckAmuck''.
* ''WesternAnimation/AroundTheWorldWithWillyFog'' is a FunnyAnimal spiritual successor to the Australian cartoon ''WesternAnimation/AroundTheWorldInEightyDays''. Considering both are based on [[Literature/AroundTheWorldInEightyDays the original book by]] JulesVerne, this should come as no surprise.
* ''WesternAnimation/TheMarvelousMisadventuresOfFlapjack'' is one to ''WesternAnimation/TheGrimAdventuresOfBillyAndMandy'' As Cartoon Network's BlackComedy shows.
* ''WesternAnimation/AdventureTime'' is considered by many people to be the spiritual successor to the first 3 seasons of WesternAnimation/SpongeBobSquarePants, as it shares many of the same writers and creativity as those seasons. It's also the successor to [[Creator/DePatieFrelengEnterprises De Patie-Freleng 's]] ''WesternAnimation/HereComesTheGrump''.
* ''WesternAnimation/LoonaticsUnleashed'' to ''WesternAnimation/RoadRovers''. Both are action cartoons with some comedy elements based on futuristic anthropomorphic superheroes, and are both made by Warner Bros. [[{{Expy}} Also, there's a number of character similarities.]]
* ''WesternAnimation/TheBoondocks'' is sometimes said to be this to ''WesternAnimation/{{Coonskin}}''.
* While ''WesternAnimation/{{Mad}}'' is more of a spinoff to ''Series/{{MADtv}}'', it's somewhat of this trope to ''WesternAnimation/KaBlam'', featuring many of the same staff (mainly a different cast as well, save for June).
* ''WesternAnimation/TheAmazingWorldOfGumball'' to ''WesternAnimation/{{Chowder}}'' as primarily evidenced by the SurrealHumour.
* ''WesternAnimation/UncleGrandpa'' to ''WesternAnimation/SecretMountainFortAwesome'', which is itself a successor to the original Uncle Grandpa short for Cartoonstitute.
* ''WesternAnimation/MoralOrel'' is an ironic- and ''very'' [[BlackComedy dark]]- successor to ''WesternAnimation/DaveyAndGoliath''.
* ''WesternAnimation/LloydInSpace'' and the 2010 reboot of ''[[WesternAnimation/PoundPuppies2010 Pound Puppies]]'' to ''WesternAnimation/{{Recess}}''.
* ''WesternAnimation/FostersHomeForImaginaryFriends'' and ''WesternAnimation/MyLittlePonyFriendshipIsMagic'' to ''WesternAnimation/ThePowerpuffGirls'', which isn't too surprising, considering that Creator/LaurenFaust worked on all 3 shows, and that her husband, Creator/CraigMcCracken, created two of those shows.
* ''WesternAnimation/MyLittlePonyEquestriaGirlsRainbowRocks'' appears to be one for ''WesternAnimation/{{Jem}}''.
* ''WesternAnimation/DannyPhantom'' to ''WesternAnimation/TheFairlyOddparents''. (The first 3 seasons anyway)
* ''WesternAnimation/TheFlintstones'' to ''Series/TheHoneymooners'', deliberately.
* ''WesternAnimation/InspectorGadget'' to ''Series/GetSmart''.
* ''WesternAnimation/HeyArnold'' can be seen as one to the Creator/{{Nickelodeon}} movie ''HarrietTheSpy''. Both involve kids living in a big city that resembles New York, adventures, eccentric kids in their grade, and eccentric people in the neighborhood. Makes sense, since ''Hey Arnold!'' was a theatrical short when the movie was released.
* ''WesternAnimation/ExoSquad'' to ''Anime/{{Robotech}}''. The viewers weren't the only ones to notice. Creator/PlaymatesToys released a short lived toyline which blended the two.
* ''WesternAnimation/YoungJustice'' is the spiritual successor of ''WesternAnimation/TheSpectacularSpiderman''?
* ''WesternAnimation/{{Gargoyles}}'' to ''WesternAnimation/AdventuresOfTheGummiBears''. Gargoyles was even originally intended to be a comedic spin-off of the earlier show, before it was retooled to its more serious, arc-driven form.
* ''WesternAnimation/KiddVideo'' could be TheEighties incarnation of ''WesternAnimation/YellowSubmarine''. for a lot more reasons than the Kiddmobile just happening to be yellow.
* In terms of role, ''WesternAnimation/PhineasAndFerb'' could be considered this to ''WesternAnimation/KimPossible''. Both were among the most successful Disney animated shows of the millennium, with its lampshade-heavy humor and similar tone at certain points.
* ''WesternAnimation/BimblesBucket'' is very much is this to ''WesternAnimation/TheDreamstone'', with a very similar dynamic, tone and even most of the characters [[{{Expy}} resembling those of the previous show]]. Both were projects created by Mike Jupp and Martin Gates Productions, meaning a good amount of the same people worked on both series.
* ''WesternAnimation/TeenageMutantNinjaTurtles2012'' shares much of the aesthetic qualities, storyline aspects, and humor as ''WesternAnimation/TeenTitans'', another series that Ciro Nieli executive produced, down to having at least [[KnightOfCerebus one villain that's darker than the rest]].
* ''WesternAnimation/RobotChicken'' is this to ''[[ComicStrip/TwistedToyfareTheatre Twisted Toyfare Theater]],'' since its made by some of the same people.
* ''WesternAnimation/TheVentureBrothers'' to ''WesternAnimation/TheTick.'' They share a creator/writer (Jackson Publick), an actor/voice actor (Creator/PatrickWarburton), and numerous themes (including various genre [[{{Deconstruction}} deconstructions]].) Tick creator Ben Edlund is also the only person to write an episode ("¡Viva los Muertos!") of the Venture Brothers outside of creators Publick and Doc Hammer.
* ''WesternAnimation/GravityFalls'' to ''WesternAnimation/PhineasAndFerb'' despite their FandomRivalry, as ''Gravity Falls'' shares similar humor, characters and atmosphere to the latter (albeit darker in humor and tone). Ironically, however, both shows would actually end up concluding within ''months'' of each other, in early 2016 and 2015, respectively. 2015 also saw the rise of ''WesternAnimation/StarVsTheForcesOfEvil'', which is also a spiritual successor to both. It has similar characters and the quirky, energetic and upbeat tone and humor of ''Phineas and Ferb'', but can also delve into dark territory at times like ''Gravity Falls''.
** ''Gravity Falls'' is also one to ''Series/EerieIndiana'' which has a pair of kids investigating the oddities in a weird town.
* ''WesternAnimation/GeneratorRex'' to the first ''WesternAnimation/BenTen'' series, both by Man of Action studios.
* ''WesternAnimation/TheBookOfLife'' to ''WesternAnimation/ElTigre'': [[RuleOfThree same creators, same theme of a family with generations of awesome, same theme]] of loving, respecting, and remembering the dead.
* ''WesternAnimation/StevenUniverse'' to ''WesternAnimation/ThePowerpuffGirls'' and (to a degree) ''WesternAnimation/TeenTitans''. All three are acclaimed superhero-type Cartoon Network shows with some anime inspirations.
* ''WesternAnimation/StarWarsRebels'' to ''Series/{{Firefly}}''
* ''WesternAnimation/{{Archer}}'' shares both multiple actors, and quite a few themes, with ''Series/ArrestedDevelopment''. It also has a similar look and feel to another series it's crew worked on, ''WesternAnimation/FriskyDingo''.
* ''WesternAnimation/OggyAndTheCockroaches'', ''The Daltons'', ''WesternAnimation/ZigAndSharko'', ''WesternAnimation/HubertAndTakako'' and ''WesternAnimation/{{Grojband}}'' to ''WesternAnimation/SpaceGoofs''.
* ''WesternAnimation/SpaceGoofs'' to WesternAnimation/TheRenAndStimpyShow.
* ''WesternAnimation/CodeLyoko'' to ''Series/VRTroopers''.
* ''WesternAnimation/SonicUnderground'' borrows a fair amount of plot details and character designs from Sonic's previous AnimatedAdaptation ''WesternAnimation/SonicSatam''. Even some of the creative team and voice crew came in to reprise their positions.
* ''WesternAnimation/GetBlake'' to ''WesternAnimation/KidVSKat'' which focuses on a KidHero and his best friend fighting against AlienAnimals, in this case alien squirrels.
* ''WesternAnimation/SonicBoom'' is basically ''WesternAnimation/AdventuresOfSonicTheHedgehog'' in CG and using more recent characters from the ''Sonic the Hedgehog'' franchise.
* ''WesternAnimation/WanderOverYonder'' to ''WesternAnimation/FostersHomeForImaginaryFriends'' and ''WesternAnimation/ThePowerpuffGirls''. They're all by Craig [=McCracken=], after all.
* ''WesternAnimation/WeBareBears'' has been compared favorably to ''WesternAnimation/EdEddNEddy''.
* ''WesternAnimation/IvanhoeTheKingsKnight'' to ''WesternAnimation/YoungRobinHood''.
* ''WesternAnimation/TeenTitansGo'' to ''WesternAnimation/AquaTeenHungerForce'', both of them being SurrealHumor type cartoons.
* ''WesternAnimation/AllGrownUp'' can be seen as one to ''WesternAnimation/AsToldByGinger''. They're both realistic, SliceOfLife cartoons done by Creator/KlaskyCsupo that have middle school aged protagonists.
* ''WesternAnimation/{{Brickleberry}}'' to ''WesternAnimation/DrawnTogether'' as they both share the same kind of [[GrossoutShow jokes]] and [[BlackComedy humor]].
* ''WesternAnimation/BubbleGuppies'' to ''WesternAnimation/TheBackyardigans''. They're both preschool aimed Nicktoons with a colorful cast and a lot of singing,
* ''WesternAnimation/KimPossible'', to a certain degree, is one to ''WesternAnimation/DarkwingDuck''. ''Kim Possible'' is also seen as Disney's take on ''Series/BuffyTheVampireSlayer:'' swap Buffy for Kim, Xander for Ron, Cordelia for Bonnie, Faith for Shego, vampires for spies and you have the basic skeleton. Throw in the meta humor and genre savvy of both series it's clearly a huge influence.
* In an odd case, ''WesternAnimation/TronUprising'' is ''technically'' set in ''Film/TronLegacy'''s timeline, but the tone and the relationship between Tron and Beck sets it as a "close enough" follow up to the sequel ''Legacy'' overruled - ''[[{{Tron20}} Tron 2.0]]''
* ''WesternAnimation/GravityFalls'', ''WesternAnimation/AdventureTime'', and ''WesternAnimation/RegularShow'' to ''WesternAnimation/TheMarvelousMisadventuresOfFlapjack'', since Alex Hirsch, Pendleton Ward, and JG Quintel all worled on ''Flapjack''. ''Regular Show'' could also be seen as one to ''WesternAnimation/CampLazlo'' too, as Quintel worked on it as well.
* ''WesternAnimation/TheLoudHouse'' to ''Series/StuckInTheMiddle'' which focuses on the antics of a very large family.
* Among Creator/{{Teletoon}}'s works, we have ''Freaktown'' to ''WesternAnimation/JimmyTwoShoes'' to ''WesternAnimation/TheBaskervilles''. The former two share the idea of ThreeAmigos (a fun-loving NiceGuy, a dope, and a smart girl) in a town populated by monsters under the tyranny of a cruel ruler (And some lesser similarities) while the latter two revolve around upbeat humans in a Hell-like town ruled by a not-Satan trying to make everyone unhappy.
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