Being a show focused on otaku, [[LightNovel/OreNoImoutoGaKonnaNiKawaiiWakeGaNai Ore Imo]] has tons of these:

* In the pilot episode of the anime, when Kirino shows Kyousuke her large stack of H-games, several real-life titles can be spotted in said stack, including (but possibly not limited to) ''[[VisualNovel/SchoolDays School Days, Summer Days, and Cross Days]]'', ''VisualNovel/AkaneIroNiSomaruSaka'', and ''VisualNovel/DaCapo''. Naturally, all of these titles have [[IncestIsRelative varying degrees]] of BrotherSisterIncest.
* Though their boxes are nowhere to be seen, Kirino also refers to ''Manga/{{Saikano}}'' and ''Anime/TengenToppaGurrenLagann'' by (partial) name -- "Tengen Toppa [[LightNovel/SisterPrincess 12 Sisters]]". This is in addition to an actual ''Sister Princess'' game box that can be seen in her closet.
%% ''Kiss X Sis'' was cut from the wiki for violating the content policy.
%% Do not restore the pothole or attempt to recreate the page.
* In the initial shots of Kirino's closet, a DVD box set of "Sis×Sis" can be seen, referring to ''kiss×sis''.
* The preload screen for the otaku website is of two characters from [=NekoSis=], another work by the same author and artist.
* [[ZetaGundam Bajeena]]... really, Saori?
-->"It's not even funny as a joke. Call yourself Psyco Gundam or [[MobileSuitGundam Big Zam]] from now on."
* That clip from Maschera we're shown features some guy who looks like a cross between [[Anime/DarkerThanBlack Hei]] and [[Anime/CodeGeass Lelouch]] (who is apparently called [[NamesTheSame Lushi]]). The mask he was wearing is reminiscent of the mask worn by the masked men/[[spoiler:the Liese twins]] in ''Anime/MagicalGirlLyricalNanohaAs''.
* Yamanashi Ganma? As in Kisaragi Gunma? Or am I mistaken?
* And the named company Alice+ is a possible portmanteau of Alicesoft and Nitroplus.
* "Siscalypse" carries a few ''LyricalNanoha'' references, notably the magic circles and "Stand by, ready."
* [[Manga/DeathNote "Just as planned."]]
* [[VisualNovel/FateStayNight Kate/Starry Night]]
** With a StealthPun to the NoExportForYou. [[spoiler: ''Unlicensed'' Blade Works]]
* Kyosuke references the [[SengokuRance Rance]] series of games when he told Manami that he'd show her his ''Hyper Weapon''.
* While singing along to the opening song to Stardust Witch Meruru, Kirino does [[MacrossFrontier Ranka Lee's]] "Kira☆!" gesture twice. This is possibly also a nod (and maybe a subtle hint about how Kirino truly feels) to [[Creator/YuuichiNakamura Kyousuke's]] [[ActorAllusion voice actor]] having played Ranka's love interest in that show.
* In the manga, [[LightNovel/ACertainMagicalIndex Misaka Imouto]] makes an appearance.
* The opening title sequence mimics the typical style of eroge openings, particularly when introducing the main characters (this is usually done with the names of their voice actors as well) OrSoIHeard.
* The ShowWithinAShow Meruru is clearly a ShoutOut to ''LyricalNanoha'', complete [[Creator/YukariTamura with her voice actress]] [[WaveMotionGun and the wave motion guns.]]
** Actually, Meruru is half a parody of Nanoha, and half a parody of HeartCatchPrettyCure, because one, the civilian forms of the girls are a parody of Tsubomi and Erika, and the opening parodies the scene in the Heartcatch opening where they are walking to school and talking.
** Episode 15 fits in one last ''Nanoha'' ShoutOut with ''[[Anime/MagicalGirlLyricalNanoha Stardust Witch Meruru The Movie 1st]]''.
** The 3rd Season is called 3rd Impact, reference to [[Anime/NeonGenesisEvangelion Neo Genesis Evangelion]]
* When Kyosuke gets lamped by Ayase in episode 10, he spins through the air in the same way as Taichi does in CrossChannel and ''Nanaca Crash''.
* The two games that Kirino wants Kyousuke to buy in episode 12 are ParodyNames of actual H-games already in the market, namely as "''3D Custom Imouto''" being a one-word swap of ''3D Custom Girl'' and "''I'd never steal something like Onii-chan's pantsu''" (three guesses).
* In Episode 12, when Kyousuke finished talking to Saori, she said [[Manga/HaruhiChan Nyoro~n]]
* During episode 5, when Ayase is having a... freakout... she yells over and over about lies, and how she hates lying. The next day, what flashes on the screen for a moment? [[VisualNovel/HigurashiWhenTheyCry A cicada.]]
* Sena "Mystic Eyes" apparently have [[MagicalEye mystic eyes]] that can [[VisualNovel/{{Tsukihime}} see the death]] of anything digital. When she [[VisualNovel/{{Tsukihime}} takes off her glass, they are as good as dead. No...deader than dead.]]
* A poster in the games clubroom says "Rosen Jungfrau". [[RozenMaiden ''Jungfrau'' just happens to mean "maiden" in German...]]
* There are games [[ called "Imouto 2", [=SistASist=] and "Final Sister IV"]] in Kirino's closet, which reference [[VideoGame/EarthBound Mother 2]], {{VideoGame/LiveALive}} and [[Franchise/FinalFantasy Final Fantasy]]. There's also the consoles' names, like Super Siscom ([[SuperNintendo Super Famicom]]) and Mintendu CS (NintendoDS). And that's not even getting into the ones written in Japanese, like [[Franchise/SuperMarioBros Super Mario Sisters]] and [[VideoGame/SecretOfMana Sister Densetsu 2]].
* From the first DVD commentary of the Vol. 7 BD is this little gem:
--> '''Kyousuke (as Lucifer from Maschera)''': I don't see anything wrong with the mascot character turning into the villain halfway through the show. It's a common trend these days.
--> *cut to a thought bubble showing [[Anime/PuellaMagiMadokaMagica Kyubey]]*
* The Games Research Club room in episode 13 has copies of hobbyist boardgames [[ Stronghold]] and [[ El Grande]] on the shelves.
* Probably Crunchyroll sub only (from season 2 episode 1):
--> '''Kirino:''' "I sense a [[Webcomic/{{Homestuck}} god-tier]] game!"
* The game that Kirino plays in the second episode of Season 2, ''Love Touch'' is a parody of ''LovePlus''
* When Kirino takes Ria to Akihabara in Episode 4 of Season 2, there's a brief close-up of a cabinet filled with SwordArtOnline figures.
* In the second anime series there is a GalGun poster on the wall of the clubroom.
* The image of Kyousuke taking Kirino on the back of a bicycle while she wears a frilly dress was eerily reminiscient of how Haruka would take Sora in ''VisualNovel/YosugaNoSora''.
* A couple minutes into the sixth episode of season two, Kouki Mikagami's shop at Comiket has two [[Anime/{{TengenToppaGurrenLagann}}very familiar-looking drill]] earrings.
* Episode 14 of Season 2 has posters of ''VisualNovel/KoihimeMusou'' and its remake ''Shin Koihime Musō'' in the same location.