* Bowling is apparently a huge deal in ''Manhua/BowlingKing''. No, seriously. Professional bowlers are all either incredibly badass or {{Bishonen}} prettyboys. Oh, and then there's how main character Shautieh Ley's ultimate goal seems to involve taking over the world with bowling somehow; while this isn't explicitly stated, chapter opening pages tend to feature things like a RushmoreRefacement where ''all'' of the faces are Shautieh (and similar ones with the Sphinx, etc.) and Shautieh disrupting other sports events.
* Creator/DCComics had a [[UsefulNotes/TheGoldenAgeOfComicBooks Golden Age]] hero called Manhunter, then bought another Golden Age hero called Manhunter. In a {{Retcon}}, the two men had an argument over who got to keep the name, and they settled it by having one of them ''go to [[AlternateUniverse another universe]]''. This a LampshadeHanging on how writers in comics loved to remove problems by having them turn out to take place in alternate universes.
* ''ComicStrip/KnightsOfTheDinnerTable'' has roleplaying games as serious business.
** "You don't understand man." "He TOUCHED my dice!"[[note]]Ask any hardcore gamer in Real Life. Touching someone else's dice/mini/whatever without permission can be considered a breach of etiquette, and with some players, is indeed Serious Business.[[/note]]
* In one ''ComicStrip/CalvinAndHobbes'' strip, Calvin throws an enormous hissy fit after losing a game of checkers to Hobbes, culminating in him passing out in exhaustion. When Hobbes points out that it's just a game, Calvin cheerfully replies: "I know! You should see how I act when I lose in real life!"
** Chewing gum is Serious Business in the ''ComicStrip/CalvinAndHobbes'' universe. Calvin is an enthusiastic reader of a magazine called "Chewing" which is dedicated to it, and informs an incredulous Hobbes that as many as twelve such publications exist.
** So is a SnowballFight.
** And he treats his snowman creations like modern art. Though he certainly puts more thought into them than most kids. This is [[CloudCuckooLander Calvin.]] ''Everything'' comes to life, and most of it [[EverythingTryingToKillYou tries to kill him.]]
* ''{{Peanuts}}'':
** An early strip had Lucy repeatedly shouting "OLLIE-OLLIE-OXEN-FREE!" Violet came by and pointedly told her that the expression was "Ollie-Ollie-''All''-''are''-''out''-''in''-free." This left Lucy more thoroughly humiliated than she'd ever been in her life.
** Once, when Lucy caught Linus about to throw a snowball at her, she angrily demanded that he take that very snowball apart ''snowflake by snowflake''. ("No pieces! No chunks! One snowflake at a time!") Poor Linus was out in the snow until nightfall.
** Linus and his blanket. When he had to go without it for a couple of weeks, he fainted several times...''in a single day''.
** Linus also had a pretty intense crush on his teacher, Ms. Othmar. When she was fired for going on strike, he threw an enormous tantrum and vowed to turn the whole matter into a federal case. He also snottily told his substitute teacher that, sure, he'd learn the lessons the way ''she'' taught them, but she still wasn't Ms. Othmar.
** Schroeder. How dare you mock Beethoven in his presence!
* ''ComicBook/{{Bookhunter}}'' takes place in an alternate-universe 1970s where books and libraries are so important that a branch of the police is devoted to investigating library-related crime.
-->'''Agent Bay:''' In many respects the American Library has become the most basic First Amendment institution. We are guards, yet we guard no less than the sum of human knowledge. We are the library police.
* ''ComicStrip/TheFarSide'' once had a ShowdownAtHighNoon having ended in defeat for the older cowboy, treating it with all the gravity you'd expect... except it was at ping-pong.
-->'''Older gunslinger''': Well, you won. Now every player in the world will come after you, looking to make a name for himself... Welcome to Hell, kid.
* [[http://dilbert.com/dyn/str_strip/000000000/00000000/0000000/000000/00000/7000/100/7165/7165.strip.gif This]] ''{{ComicStrip/Dilbert}}'' strip illustrates how to apply the principles of SeriousBusiness in the workplace.
** This comic was based on one of Scott Adams' coworkers, who actually said "I will fight you to the end of the earth!" To him, it was serious business.
* In ''ComicBook/WelcomeToTranquility'' Captain Cobra and Mongoose Man are not just enemies, but "enemies to the DEATH." Unfortunately, their advancing years are actually bringing them pretty close to that goal line and they have both retired from super-activities, heroic and villainous alike. So, what is left for them to be enemies over? Why, the apple tree that looms over both their properties, and who has proper ownership over the apples that fall down on either side of their fence. Just ask Sheriff Lindo, apples are ''serious business''.
* Beef is Serious Business in the CrapsackWorld of ''Comicbook/GiveMeLiberty''. Fast-food restaurants wage wars for farmland, people commit suicide for hamburgers, and there's even a 94th Amendment outlawing red meat.
* [[http://comics.com/pearls_before_swine/2010-01-17/ Board games]] are apparently serious business to Rat in ''Comicstrip/PearlsBeforeSwine''.
* The people of a Hannoverian village who want to celebrate the birthday of their ex-king (Hannover was conquered by Prussia in 1866; some people nursed a grudge because of this, and pro-Prussian Creator/WilhelmBusch wrote this story as a TakeThat).
* One ''Cthulhu Tales'' comic had an unnamed "Maine Cheetahs" baseball fan ([[BlandNameProduct according to Google, no such team exists]]) for whom baseball was ''such'' serious business, he went so far as to ''invoke Cthulhu'' in order to win them their first World Series in seventy years. [[EldritchAbomination It doesn't appear to end well for anyone concerned]].
* In the German comic ''ComicBook/{{Werner}}'': Brewing beer, tuning bikes %% This entry was added automatically by FELH2. In case the wording doesn't make sense, rewrite it as you like, remove this comment and tell this troper.
* The "Sorry Cake" in Issue #3 of ''ComicBook/MyLittlePonyFriendshipIsMagicIDW'':
-->'''Pinkie Pie:''' Luckily, I always travel with an "I'm sorry" cake! I also have "I am sorry" goodie bags!\\
'''Twilight Sparkle:''' Uh, Pinkie, I don't think we have time for cake... we are only an hour away from the Changeling kingdom...\\
'''Pinkie Pie:''' '''EAT... THE... CAKE.'''
* When WonderWoman was stuck working at [[BurgerFool Taco Whiz]], she took the job very seriously. Then again, she takes everything seriously, except Franchise/{{Batman}}'s brooding.
* According to the ''BatmanTheAnimatedSeries'' "Mad Love" comic, TheJoker takes comedy ''very'' seriously. Only ''he'' gets to tell jokes during his crimes; he throws a tantrum if anyone else makes a crack. And if people don't understand one of his gags and [[DontExplainTheJoke he has to tell them why it is funny]], that takes all the fun out of it - even if it involves killing Batman.
-->'''Joker''' ''[angrily, to Harley Quinn]'': My jokes are elegant in their simplicity. You see them, you get them, you laugh - end of joke! You should have remembered when I told you that a long time ago; it's one of the few real truths of comedy!...''You're always taking shots from folks who just don't get the joke!'' [[note]] Admittedly, this is a very sensitive IronicEcho for the Joker because it was, verbatim, what he had told Harley earlier after relating to her the story of his father [[AbusiveParents breaking his nose and putting him in the hospital]] when he was a boy because he was angered by a prank the young Joker tried to play on him - but then again, Batman points out that the story is most likely a lie. [[/note]] ''[strikes Harley repeatedly with a large fish, [[DisproportionateRetribution sending her crashing through a high window and down to the street far below]], nearly killing her]''
** There's also the ''Adventures of Batman & Robin'' (a Saturday morning spinoff show of the above) episode "Make 'Em Laugh." The Joker is outraged because a panel of three comedians won't give him the annual trophy for best comic in Gotham City (despite the fact that he wasn't even eligible to compete because registration had already ended), so he 1) steals the Mad Hatter's mind-control microchips at Arkham and puts the Hatter himself in a microchip-induced coma from which he might never wake up; 2) kidnaps and brainwashes the three comedian-judges, turning them into super-criminals and indirectly getting one of them sent to the hospital with life-threatening injuries; and 3) replaces the judges with three of his own men, forces the emcee to introduce him as the ''only'' contestant, and terrifies the audience by juggling grenades until Batman and Robin show up. Batman scolds him for ruining so many people's lives just because he couldn't get a cheap trophy.
* The ''Franchise/{{Batman}}'' comics - and, by extension, almost all ''Batman'' media - have this as their unspoken premise. Other cities are plagued merely by gangsters, drug dealers and riots; Gotham City has all those problems ''and'' a relatively large segment of the population consisting of the most psychopathic and vicious men and women on the face of the earth - [[PsychopathicManchild who also have childishly costumed alter egos]]. In a way, [[FridgeLogic it's sad when you think about it]]: not only are the lives of Gothamites constantly in danger, but [[SubvertedInnocence their innocence has also been destroyed]]. They will never be able to find clowns funny, to think penguins are charming, or to consider riddles an entertaining mental exercise. (And in the [[Creator/TimBurton Burton]]/[[Creator/JoelSchumacher Schumacher]] movies, too: How will those people ever again be able to see a parade balloon or a Christmas tree-lighting without suffering psychological trauma? [[ParanoiaFuel How can they ever even watch TV, now that they know that some megalomaniac could literally be using their cable box to read their brainwaves?]]) And all the while, Batman and the Gotham police alike have to treat all of this ''very'' seriously, perhaps at the risk of losing their sanity. Harvey Bullock once pointed out that [[HeWhoFightsMonsters it was a miracle they all weren't as crazy as the nutjobs they fought]]. Commissioner Gordon once suggested that various members of the Rogues Gallery (in this instance, Maxie Zeus, who literally believes he is a Greek god) would be [[NotSoHarmlessVillain really absurd and even pathetic if they weren't so dangerous]]. And Batman himself has remarked that, [[LampshadeHanging as cheesy as the concept of Ra's Al-Ghul destroying the world might sound]], he is dead serious about doing just that - and one terrible day, he might succeed.
* ''ComicBook/{{PS238}}'':
-->"You have wronged innocents, Charles. I formally challenge you to a game of [[http://en.wikipedia.org/wiki/Four_square four-square]]. The loser will be given over to the lords of this realm to do with as they please!"