''Mr. Brain'' is a Japanese television [[{{dramedy}} comedy drama]] aired on TBS in 2009.

Sypnosis by TBS (retrieved from ''[[http://wiki.d-addicts.com/MR._BRAIN wiki.d-addicts.com]]''):

Tsukumo Ryusuke is a quirky, yet brilliant neuroscientist working for the National Research Institute of Police Science. Wielding a unique perspective and psychology, Tsukumo tackles the nation's most baffling crimes and scandals, going head-to-head with the most brilliant and twisted criminal minds. But his eccentricities and poor social timing can also aggravate people and circumstances, further complicating matters.

!!This show provides examples of:

* AccidentalMisnaming: Detective Hayashida is frequently called "Rinda" by Tsukumo.
* AmateurSleuth: Tsukumo, who tends to get chastised by his boss for not concentrating on his "research".
* AxCrazy: Kanako in her "Shunsuke" persona.
* BatmanGambit:
** Tsukumo relies on the culprits' "natural reflexes" (caused by their brains) to expose them.
** The culprit's schemes in the last two episodes.
* BigEater: Kanako in her "Shouko" persona.
* BunnyEarsLawyer: Tsukumo, a brilliant ''and'' eccentric neuroscientist.
* ButtMonkey: Kazune.
* {{Catchphrase}}: "My name is Tsukumo, written as 9-10-9 in kanji numerals."
* ChasteHero: Due to partial brain damage caused by an accident, Tsukumo is totally clueless about Kazune's advances on him, and keeps wondering why he's in possession of a porn magazine in the first place.
* EveryoneCallsHimBarkeep: The cleaning lady.
* ExactlyWhatItSaysOnTheTin: The show has some very specific episode titles, including:
** "Eccentric Neuroscientist vs. Beautiful Revived Ghost!!"
** "Invisible Man Setting Up Serial Murders!!"
** "Eccentric Neuroscientist vs. Beautiful Woman With A Split Personality!!"
* {{Expy}}: Takegami is a manipulative cannibalistic murderer like Hannibal Lecter.
* FragileFlower: Kanako's original persona.
* ImAHumanitarian: In the second episode, {{Gackt}}'s [[LargeHam ham]]-tastic character Takegami Teijirou is a cannibalistic serial killer who considers eating human flesh to be the equivalent of eating beef or pork.
* InsufferableGenius: Even though Tsukumo Ryusuke usually figures out the crimes long before anybody else, he is still considered insufferable by many of his superiors.
* GigglingVillain: Takegami Teijirou.
* KidsAreCruel: Kanako's classmates ridiculed her request for accompanying her home, resulting in her kidnapping.
* LargeHam: It's obvious {{Gackt}} is [[http://www.youtube.com/watch?v=V6dwJaSDcYI having a lot of fun]] playing a cannibal.
* NoSocialSkills: Part of the reasons why many other scientists dislike Tsukumo.
* NotMyDriver: Happens to a victim in Episode 7.
* ObviouslyEvil: Takei, who's [[BaldOfEvil bald]] and is frequently seen with a [[SmugSmiler smug smile]] on his face. [[spoiler: He's actually a case of double subversion of this trope]].
* PosthumousCharacter: Takegami Teijirou.
* PsychoticSmirk: Takegami loves to sport this.
* RealSongThemeTune: "Jump" by Music/VanHalen.
* RoaringRampageOfRevenge: Some of the culprits.
* ShrinkingViolet: Yuri Kazune, although she does have a few moments of assertiveness. Not that anybody listens to her when she does, though.
* SplitPersonality: Akiyoshi Kanako suffers from this after being kidnapped and imprisoned for 15 years. [[spoiler:Then it turns out there are actually no alternate personalities to begin with]].
* TrademarkFavoriteFood: Tsukumo has his bananas.