* Kyon's theme song from ''LightNovel/HaruhiSuzumiya'' includes one of these for no apparent reason (he NEVER does this in the manga or anime).
* Gintoki of ''Manga/{{Gintama}}'' fame occasionally lets out a comical scream of this nature when he's subjected to something he finds particularly horrifying. Said incidents include:
** Listening to an otherwise relaxing radio story with some SurpriseCreepy at the end.
** His balls getting detached by Doman immediately after Seimei reattached them in the aftermath of a nasty GroinAttack.
** Provoking Kagura's wrath by mistaking her being bashful about giving him Valentine's chocolate for her being constipated.
* ''Anime/CodeGeass'': Even anti-heroes scream in high-pitched [[http://www.youtube.com/watch?v=tiwYeihYwgw voices]]
* Nozomu's "IIIIIIYYYYYYAAAAAAA!!!!!!" from ''Manga/SayonaraZetsubouSensei''. One of the funniest instances is when he does this after the girls see him naked during the HotSpringsEpisode, and the DeadpanSnarker Abiru lampshades that "that should be our reaction".
* [[TheDitz North Italy]] in ''Webcomic/AxisPowersHetalia'' at one point screams "Kyaaaa!". [[HeroicWannabe America]] as well.
** Greece in the dub of season 3, when Japan pretends to pull his thumb off.
** Romano shows off his manly screech in the dub, when both he and his brother are caught by England. Actually, he does this a lot.
** Finland in the dub of season three too, from the "Running Away with Mr Sweden" episode.
* Zoisite does this when he discovers that he is surrounded by rats in the original Japanese version of ''Anime/SailorMoon''. Aside from his relationship with Kunzite, this was one of the main reasons he was turned into a girl for the Creator/DiC version.
* Early in ''Manga/AzumangaDaioh'', a war against a cockroach begins after a very high-pitched scream erupts from one of the students. Afterward, it's revealed the source of that scream was Sakaki who, while being an actual girl, is also an AloofDarkHairedGirl and normally has a deep voice.
* Ramiel, an EldritchAbomination made from impossible geometric shapes, in ''Anime/RebuildOfEvangelion''. ''Definitely'' not PlayedForLaughs.
* In the ''Anime/{{Pokemon}}'' anime, Cilan lets out a [[http://www.youtube.com/watch?v=qze5PJ7l0KQ very girly scream]] in one episode.
* From episode 18 of ''Anime/YuGiOhGX'':
-->'''Jaden:''' ''(Crowler screams offscreen)'' Someone's in trouble!\\
'''Bastion:''' Let's go help her!
* In any {{Ecchi}} anime, whenever the guy walks in on a girl taking a bath, you'd expect the girl screaming at the guy. This is not the case in ''LightNovel/HighSchoolDXD'' when Issei walks in on the bathroom while Asia was still inside. ''He's the one'' screaming and trying to cover himself instead of the other way around.
* In Manga/ExcelSaga, when Iwata [[ItMakesSenseInContext finds himself in Ropponmatsu II's]] body, his first reaction is to proclaim "HIGH PITCHED GIRLISH SHRIEK!!"
* Tubby screamed this way in most episodes of the ''Anime/LittleLulu'' anime, most notably in Episode 2.
* Mamoru from ''Literature/FromTheNewWorld'' does this in episode two, and Maria scolds him about it.
-->'''Maria:''' Don't cry like a little girl!
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