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* Twin sisters of the NasuVerse, Aoko and Touko, are this. One is chaotic, the other lawful. Touko was originally depicted as having blue hair until the ''{{Kara No Kyoukai}}'' {{OAV}} gave her an AdaptationDyeJob to resemble her ''twin'' sister more. Genetics beats out symbolism these days. Nevertheless, their Mage Titles are "Red" and "Blue". (Don't bring it up, it's a sore subject.)
** Inverted in terms of their titles. Aoko exhibit the traits of red but her title is "Blue" (since the color blue is associated with her magic) and visa versa for Touko. Aoko's name also comes from the Japanese word for blue, "Aoi."
* In ''FateStayNight'' Rin and Saber are this.
** Slightly played also with Archer and Lancer by their color scheme, but their personalities are exactly the opposite.
* Mion of ''VisualNovel/HigurashiWhenTheyCry'' has a tattoo of a blue oni, prominently featured in the opening. However, she's far more like the red oni in terms of personality. [[spoiler:Then again, the tattoo isn't "hers" to begin with, thanks to an unfortunate TwinSwitch in which ''Shion'' was supposed to get it. As a result, Mion is supposed to act ''Red'' as part of the ''older'' sibling role she's forced to play, while her sister Shion acts ''Blue'' as part of the ''younger'' sibling's role. In truth, Mion's true self is blue while Shion's is red]]
** Also, in episode 20 of ''HigurashiNoNakuKoroNiKai'', [[spoiler:Hanyuu]] says "If [[spoiler:Keiichi]] is a flame that burns red, then [[spoiler:Rena]] is a quiet, blue flame!"
** Keiichi (red) also has this relationship with Mion (blue) to a lesser degree.
* In ''VisualNovel/UminekoWhenTheyCry'', Lambdadelta is the red to Bernkastel's blue. [[spoiler:In the first half of the series, anyway. In the second half, as their true motivations are revealed, their roles are switched around.]]
** Shannon can be seen as the red to Kanon's blue most of the time, but when it comes to matters of love Shannon is more calm and collected while Kanon is more hot blooded and irritable. [[spoiler:It is also heavily implied that they are in fact the same person, and their red and blue dynamic shows Yasu's conflicting views about love.]]
* HotBlooded fighter Kid and calm magician Magil in VisualNovel/RadicalDreamers.
* The ''VisualNovel/AceAttorney'' series has some Red and Blue Onis. An inverted example is Phoenix, the blue-clad defense attorney (who isn't as hot-headed as a typical Red Oni, but he doesn't tend to think things through) and his red-wearing frenemy Miles Edgeworth, who is calm, cool, and calculating most of the time. In fact, the lawyers with the more fiery reddish qualities (Phoenix, Franziska, etc.) have a blue motif in their dress, while the more aloof ones (Edgeworth, Godot's visor [[spoiler:and clothing as Diego Armando]]) have a red motif.
** Another example from the later game, Apollo Justice, has the title character wearing a red vest - his preference for the color red is even mentioned a couple times in-game - and being rather impulsive (also, his hair is horns!). There are a couple of blue onis in the game. Kristoph Gavin, for one, is, though friendly, very serious and icy as well and wears a blue suit. [[spoiler: However, in the end, Kristoph pretty much [[VillainousBreakdown out-hams every murderer in the series]].]] Klavier Gavin is the epitome of "cool collectedness" and wears a purplish maroon getup.
** Also from Apollo Justice, to a lesser degree, we have another inverted version with Klavier in his pinkish/reddish/purplish outfit as a cool straight-man, and his band-mate Daryan Crescend in a blue, shark-like outfit being quite temperamental.
** Another one from Apollo Justice: [[BlueOni Phoenix Wright]] is finally living up to his colour scheme and now plays the cryptic and coolheaded {{Chessmaster}} in direct contrast to [[RedOni Apollo's]] HotBlooded and flustered character.
** Also played with in ''Justice For All'': Matt Engarde, a popular - if somewhat dim - celebrity wears a scarlet jacket, whereas his manager, Adrian Andrews, is calm and collected and wears blue. [[spoiler: In reality, Engarde is a vicious, self-obsessed manipulator and Adrian is a co-dependent, frail woman who's deathly afraid of Engarde.]]
** While Phoenix and Apollo might be reds to their prosecutor rivals' blues, they also both tend to play the more rational StraightMan to to their GenkiGirl CloudCuckooLander assistants.
** And let's not forget about Robin Newman and Hugh O'Conner in ''Dual Destinies''. Robin, who is very hyperactive and likes to shout, wears red, while the calm, laid-back Hugh wears blue.
* ''VisualNovel/LittleBusters'': Haruka and Mio fit this whenever they interact, with overly emotional, [[GenkiGirl energetic]], ditzy, impulsive, ManicPixieDreamGirl-esque Haruka being the Red Oni and quiet, sly, intellectual, [[{{Kuudere}} cool]], [[TheStoic stoic]] Mio being the Blue Oni.
** Also, HotBlooded DumbMuscle Masato and his friend/rival, the [[TheStoic Stoic]], Kendo-playing Kengo. Fittingly, Masato wears a red shirt, while Kengo is almost always wearing his navy blue Kendo outfit.
* ''VisualNovel/HatofulBoyfriend'': the human girl is generally red to everyone else, with the exception of Oko San who matches her for hot blood. As brothers, [[HandsomeLech Yuuya]] and [[ShelteredAristocrat Sakuya]] are red and blue respectively.
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