After having a nervous breakdown that almost gets her time in jail, Marge goes to Rancho Relaxo while Homer watches Maggie and her sisters watch Bart and Lisa.
!!Tropes of this episode:
* AdultFear: Homer's reaction when he discovers Maggie is missing from her crib and can't find her anywhere.
* BigNo: Marge belts one out when she finally snaps.
* ClicheStorm: Invoked:
--> '''Quimby''': ...If I go down, you're breaking my fall!\\
'''Wiggum''': Quimby, don't write checks your butt can't cash.\\
'''Quimby''': Hear me, Wiggum, you bite me, I'll bite back.\\
'''Wiggum''': You talk the talk, Quimby, but do you walk the walk?
* FanDisservice: Lampshaded, discussed in-universe when Bart laments sleeping over at Selma and Pattys' and Lisa replies "You think you know fear? Well I've seen them naked!"
* GagBoobs: All Bart has to say when he spots Selma's large bra (the cup can cover his head)
--> Ay Carumba!
* GetOut: Marge gets quite annoyed by Bart and Lisa's antics while driving to school, to the point of telling them to get out in a deep, echoing voice.
* IronicJuxtaposition: When Marge returns from her trip, she holds up a picture of Homer, Bart, Lisa, and Maggie where the four are smiling; when she lowers the photo, she sees the four in a morose, exhausted state due to her absence.
* IsntItIronic: The ironic hold music that Homer listens to (and still cries over) when calling the police to report Maggie being missing is "Baby Come Back" by Player, which is a breakup song about a man begging his lover for another chance.
* JerkassRealization: Homer acts like a Jerkass, as usual, through Marge’s plight until she rolls down her window.
* KarmaHoudini: Marge gets off completely scot-free for blocking the bridge thanks to Mayor Quimby pulling some strings.
* KidsAreCruel: In the beginning, you wonder why Marge snapped.
* MightyRoar: The bus driver from Shelbyville is scared off by this.
* NervousWreck: Marge when the stress of errands gets to her -- while driving.
* NobleDemon: Mayor Quimby pulls some strings to get Marge off the hook for blocking the bridge. Granted, he didn't do it out of sympathy for Marge's stress, but because he knew he risked losing the women's vote if she went to jail.
* NotHelpingYourCase: When Patty and Selma express doubts that Homer can take care of Maggie on his own ("He'll probably trade her for a beer and a nudie magazine"):
--> '''Homer''': For your information, I can take care of my- ''(Maggie slides to the ground'') AAAH!! ''(picks her up)'' See? Got her on the first bounce.
* OddNameOut: The three movies available on Rancho Relaxo's pay-per-view service include ''Film/ThelmaAndLouise'', ''The Happy Little Elves Meet Fuzzy Snuggleduck''... and ''The Erotic Awakening of S''.
* ParentalNeglect: Homer when he's looking after Maggie, but in his defense he did try to care for her and no one saw her running off to find Marge and as soon as he knew, he looked all over for her and called the police.
* PoliceAreUseless: Though he has grounds to have her in jail, Wiggum had to let Marge go due to pressure from Mayor Quimby and he doesn’t notice the mobster with a body in the car who’s held up.
** Wiggum goes to arrest Homer for criminal neglect after finding Maggie and returning her home, but bashfully lets Homer off with a warning after Homer kisses him and thanks him for finding his baby daughter.
* PrankCall: Bill and Marty call a man and tell him his wife is dead.
* RageBreakingPoint: Maggie spilling her milk on Homer's newly-ironed shirt and on Marge while she's driving.
* RevealShot: At the end of the episode, Homer and Marge are talking in bed. You think it's just those two, but then Bart starts talking, and it's revealed that the whole family is sharing the same bed.
* SanitySlippage: Various irritations chip away at Marge's stability until she locks herself in the car on a bridge.
* ScrewTheRulesIHaveConnections: Quimby orders Marge to be freed without changes because it could cost him the women’s vote if he allows the law to go the way it’s set.
-->'''Quimby:''' They're just like seals. Throw them a fish and they start clapping their fins together.
* ShoutOut: The beginning parodies the ''WesternAnimation/WileECoyoteAndTheRoadRunner'' cartoons.
** Marge watches ''Film/ThelmaAndLouise'' on tv.
** ''The Erotic Awakening of S'' is a parody of ''The Story of O''.
** The episode's title (and Homer's both-hands-on-cheeks-and-screaming while looking at the camera pose upon discovering Maggie's disappearance) are shout outs to ''Film/HomeAlone''.