'''Season 1, Episode 13''':
!Route 666
[[caption-width-right:300:'''Sam:''' So burning the body had no effect? '''Dean:''' Sure it did. Now it's really pissed.]]

-->'''Sam:''' (over a cellphone) Where are you?
-->'''Dean:''' I'm in the middle of nowhere with a killer truck on my ass!

Written by Eugenie Ross-Leming and Brad Buckner .

Directed by Paul Shapiro.

Airdate: January 31, 2006.

An old flame calls Dean for help when a big black truck starts killing black men in [[https://en.wikipedia.org/wiki/Cape_Girardeau,_Missouri Cape Girardeau, Missouri.]]

Dean receives a call for help from an ''[[LoveInterest old friend]]'' [[Characters/SupernaturalOtherHumans Cassie Robinson]], and drags Sam to Cape Girardeau, Missouri, to investigate the deaths of two black men who had visions of a black truck before they died in unexplained car accidents. It turns out Cassie is Dean's ex-girlfriend who dumped him after he revealed his lifestyle as a hunter. The second victim was her father and the first was one of her father's closest friends.

They find out that 40 years ago several black men disappeared into a big black truck, but Cassie's mother is reluctant to discuss the past. Before they can find out more the first black reporter at the newspaper where Cassie works also dies in an odd car accident on the same road. Sam investigates the past disappearances while Dean ''investigates'' any connections to Cassie's family, which leads to Dean and Cassie in bed together. The mayor dies next, looking as if he had been run over. Later the same black truck attacks Cassie's home while she and her mother are home.

Cassie's mother then reveals that she had previously dated a [[WhiteAngloSaxonProtestant wealthy white man]] [[Characters/SupernaturalGhosts Cyrus Dorian]], but decided to marry Cassie's father, Martin, a black man, which was controversial as it was an interracial relationship. After she breaks up with Cyrus, [[LoveMakesYouEvil his personality changes]], and the stories about black men disappearing start. The church where they were to be married is burnt down, [[WouldHurtAChild killing the children]] who had [[ChildrenAreInnocent gathered for choir practice]]. But the attacks continued with the truck coming for Martin, Cassie's father. Martin is badly beaten, but manages to get free and kills Cyrus. Martin's friend's help him roll the truck [[DisposingOfABody with Cyrus' body]] into the swamp, and the mayor who was a deputy at the time covers up their actions.

Dean and Sam retrieve the body from the swamp and burn it, but then a threatening truck appears. Dean tries to distract the truck by taking off in the Impala, while Sam gives him directions over the phone. Dean follows the directions blindly and as the truck roars towards him, it disappears. Sam reveals he directed Dean to the location of the burnt down church and the spirit of the truck was destroyed when it passed over hallowed ground. Later Dean says goodbye to Cassie and mentions wanting to see her again, but Cassie says, "You know what? I'm a realist. I don't see much hope for us, Dean."

!!Body count:
For this episode = [[spoiler: 3 humans and 1 ghost]].

For the series so far = At least 126 humans; 9 ghosts; 1 god; 1 rawhead; 1 shapeshifter; and 1 wendigo.

!Tropes appearing in this episode:

* AFriendInNeed
* ArtisticLicense - Geography: Cape Girardeau is treated as a tiny, middle-of-nowhere town in the boondocks of Missouri, when in reality it boasts a large college and a population of nearly 38,000 people.
** Additionally, Route 6, a small two-lane highway, is treated as "the only road in and out of town". Interstate 55, one of the largest north-south highways in the country, runs straight through downtown Cape Girardeau.
* AssholeVictim: Cyrus.
* TheBechdelTest: Passed. Cassie's mother tells her the truth about the past.
* BlackDudeDiesFirst: And second.
* BloodFromTheMouth: Harold Todd.
* BigBadassRig
* CaptainObvious:
-->'''Sam:''' By old friend you mean...?
-->'''Dean:''' A friend that's not new.
* ChaseScene
* CrazyEnoughToWork / UnspokenPlanGuarantee
-->'''Sam:''' So I figured, maybe, that would get rid of it.
-->'''Dean:''' Maybe? Maybe!! What if you were wrong?
-->'''Sam:''' Huh. Honestly that thought hadn't occurred to me.
* CreatorBacklash: This is one of Eric Kripke's least favorite episodes.
* DeggansRule: Failed. Cassie is the only non-white main character, although Jimmy and the dock worker had speaking lines. The story is also about race.
* DespiteThePlan: This is the second time [[KillItWithFire burning the bones]] did not work. The first time was in [[Recap/SupernaturalS01E07HookMan "Hook Man"]].
* DiesWideOpen: Harold Todd.
* TheDogBitesBack: Martin Robinson.
* ElectromagneticGhosts: Static on the car radio.
* FanService:
** BareYourMidriff: Cassie in the violet top with the white belt.
** ShirtlessScene
** ShouldersUpNudity
* GirlOfTheWeek: [[LampshadeHanging Lampshaded]] by [[GenreSavvy Cassie]].
* INeverSaidItWasPoison: Dean asks the mother how does she know Cyrus died while the paper's said he went missing.
* InsistentTerminology: Dean, TheNicknamer, never calls Cassie by any other version of her name, [[spoiler: which leaves the name Cas open for Castiel.]]
* IntrepidReporter: Cassie.
* LadykillerInLove: This is the first time we've actually seen Dean fall for somebody.
* LoveCannotOvercome: Dean and Cassie.
* MalignedMixedMarriage: Cassie's parents.
* TheMasqueradeWillKillYourDatingLife: Dean tells Cassie the truth about hunting, but she thinks it is an excuse to leave her.
* MoodWhiplash: Although it generally follows the FirstLawOfTragicomedies.
* NewOldFlame: Cassie to Dean.
* NothingIsScarier: The driver of the truck. (Or lack thereof.)
* SeekingSanctuary
* SerialKiller: Cyrus.
* ShoutOut:
** The scenes with the truck chasing down the victims are reminiscent of ''Film/{{Duel}}''.
** The Car in ''Film/TheCar'' also is unable to cross the hallowed ground of the cemetery.
** The story of the burnt church is similar to the [[http://en.wikipedia.org/wiki/16th_Street_Baptist_Church_bombing 16th Street Baptist Curch bombing.]]
** Dean suggests the truck may be a FlyingDutchman.
* SimilarlyNamedWorks:
** A [[Comicbook/{{Route666}} Comic Book]].
** An [[http://en.wikipedia.org/wiki/Route_666_%28film%29 action/horror film.]]
** Two part episode of ''MarriedWithChildren''.
* SlapSlapKiss: "We should fight more often."
* TwoferTokenMinority: Cassie as a black woman.
* UrbanLegend: Stories related to the renumbered [[http://en.wikipedia.org/wiki/U.S._Route_491 Route 666.]]
* VehicularAssault
* WhoYouGonnaCall: When Cassie gets in trouble, she calls Dean.
* YourCheatingHeart: Cassie's mother was seeing Martin while dating Cyrus, and eventually left Cyrus for him.